TORC2 (Ser171) Antibody

• Catalog number
  bs-3415R
• Price
  Please ask
• Size
  0.1ml

• Long name
  TORC2 (Ser171) Primary Polyclonal Antibody
• Also known as
  TORC2 (Ser171) PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  TORC2 Ser171
• Specificity
  This is a highly specific antibody against TORC2 Ser171.
• Modification s
  Phosphorylation
• Modification site s
  Ser171
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  150-190/693
• Subcellular location
  Nucleus
• Source
  KLH conjugated synthetic phosphopeptide derived from human CREB regulated transcription coactivator 2 around the phosphorylation site of Ser171
• Gene ID number
  200186
• Swiss Prot
  Q53ET0
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates gluconeogenesis as a component of the LKB1/AMPK/TORC2 signaling pathway. Regulates the expression of specific genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR).
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  TORC2; TORC-2; CREB-regulated transcription coactivator 2; Transducer of regulated cAMP response element-binding protein 2; Transducer of CREB protein 2; CRTC2
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  TORC2   Ser171  
• Gene symbol
  CRTC2
• Short name
  Anti-TORC2 Ser171
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  TORC2 (Ser171) Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:27301
• Gene
  CRTC2
• Long gene name
  CREB regulated transcription coactivator 2
• Synonyms
  • TORC2
• GenBank acession
  • AY360172
• Locus
  1q21.3
• Discovery year
  2005-11-24
• Entrez gene record
  200186
• Pubmed identfication
  • 14506290
  • 14536081
• RefSeq identity
  • NM_181715
• VEGA ID
  OTTHUMG00000037156

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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