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anti-cIAP-1/HIAP-2 Antibody

  • Catalog number
    3180-100
  • Product name
    anti-cIAP-1/HIAP-2 Antibody
  • Size
    cIAP-1/HIAP-2 Antibody
  • Price
    338EUR
  • Supplier
    biovision antibodies-kits-proteins
  • Antibody host:
    Rabbit
  • This antibody reacts with:
    Human, mouse, rat
  • Purification method:
    Affinity purified
  • Immunogene sequence:
    Synthetic peptide surrounding amino acid 530 of human cIAP-1
  • How to handle this antibody:
    The antibody solution should be gently mixed before use.
  • Form of antibody:
    Liquid
  • This antibody has been succesfully tested for use in following methods:
    Western blot, Immunohistochemistry
  • Target of this antibody:
    cIAP-1/HIAP-2
  • Formulation of this antibody:
    100 µg (0.2 mg/ml) affinity purified rabbit anti-cIAP-1 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.
  • Alternative names of antibody target:
    API1 , cIAP1, C-IAP1 , HIAP-2 , HIAP2 , RNF48 , MIHB, IAP2, BIRC2
  • Recommended usage:
    Western blot analysis (0.5-4 µg/ml), and Immunohistochemistry (5 µg/ml). However, the optimal conditions should be determined individually. Jurkat cell lysate and rat kidney tissue lysate can be used as positive controls.
  • Storage information:
    Shelf time: 12 months in temp.: -20 deg.C
  • Shipping conditions:
    gel pack
  • Clonality of antibody:
    Polyclonal
  • Isotype:
    Rabbit IgG
  • Background information:
    Apoptosis can be inhibited by a group of proteins called inhibitors of apoptosis (IAPs). These proteins contain a BIR (baculovirus IAP repeat) domain near the amino-terminus. The BIR domain can bind some caspases. Many members of the IAP family of proteins block proteolytic activation of caspase-3 and –7. For example, XIAP, cIAP-1 and cIAP-2 appear to block cytochrome c-induced activation of caspase-9, thereby preventing initiation of the caspase cascade. Since cIAP-1 and cIAP-2 were first identified as components in the cytosolic death domain-induced complex associated with the TNF family of receptors, they may inhibit apoptosis by additional mechanisms.
  • Concentration of antibody:
    0.2 mg/ml
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
  • Properties
    If you buy Antibodies supplied by biovision antibodies-kits-proteins they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • Gene target
  • Short name
    anti-cIAP-1/HIAP-2 Antibody
  • Technique
    Antibody, antibody to, antibodies against human proteins, antibodies for
  • Alternative name
    antibody to-cIAP-1/HIAP-2 (Antibody to)
  • Alternative technique
    antibodies
1. Gene info
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