Rat CD8α Mouse Monoclonal Antibody [53-6.72]-Biotin
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Catalog numberBD-MO8AB(V25)
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Price:
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Size0,025 mg
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DescriptionRat CD8α Mouse Monoclonal Antibody [53-6.72]-Biotin is a mouse monoclonala antibody, specific for [53-6.72] clones, this product was conjugated with Biotin format and reported for use in flow cytometric analysis to react with CD8 α proteins in thymocytes, T cell subset, some NK cells, lymphoid dendritic cells, Most thymocytes, CD8 α acts as a co-TCR recptor to activate T cells, also regulate the efficience of cell-cell interactions.
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Clone53-6.72
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ConjugateBiotin
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Gene NameCD8 α
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Other Names of geneT8, Lyt2, Ly-14
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Concentration500 µg/mL
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ApplicationFlow Cytometry Method
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ImmunogenMouse thymocytes/splenocytes
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FormulationAqueous buffered solution containing protein stabilizer, and ≤0.09% sodium azide (NaN3).
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Storage2-8°C, store in dark, do not freeze
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ExpirationAfter 1 year
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RemarkFor Recherche Use Only.
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PropertiesIf you buy Antibodies supplied by Immunostep they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.
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ConjugationBiotinylated
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AboutMonoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes. Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
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TestMouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin nameMus musculus, Rattus norvegicus
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French translationanticorps
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Gene target
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Gene symbolCD8A, IGLVIV-53, IGHV3-53, IGHVII-53-1, IGFBP3, RNU6-53P, SNORD8, RBBP4, IFT52, LMAN1
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Short nameCD8α Mouse Monoclonal Antibody [53-6 72]-
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TechniqueMouse monoclonal, Antibody, Mouse, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
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HostRat, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
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IsotypeRat IgG2b
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LabelBiotin
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SpeciesMouses, Rats
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Alternative nameRat Anti Mouse CD8 α Antibody-Biotin
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Alternative techniqueantibodies, murine
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Gene info
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Identity
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Gene
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Long gene nameCD8a molecule
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Synonyms gene
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Synonyms gene name
- CD8 antigen, alpha polypeptide (p32)
- T-cell surface glycoprotein CD8 alpha chain
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Locus
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Discovery year1986-01-01
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- V-set domain containing
- CD molecules
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin lambda variable (IV)-53 (pseudogene)
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Synonyms gene name
- immunoglobulin lambda variable (IV)-53
- immunoglobulin lambda variable (IV)-53 pseudogene
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-05-08
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Entrez gene record
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RefSeq identity
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Classification
- Immunoglobulin lambda locus at 22q11.2
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin heavy variable 3-53
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GenBank acession
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Locus
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Discovery year2000-04-04
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Entrez gene record
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RefSeq identity
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Classification
- Immunoglobulin heavy locus at 14q32.33
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin heavy variable (II)-53-1 (pseudogene)
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Synonyms gene name
- immunoglobulin heavy variable (II)-53-1
- immunoglobulin heavy variable (II)-53-1 pseudogene
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-04-17
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Entrez gene record
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RefSeq identity
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Classification
- Immunoglobulin heavy locus at 14q32.33
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameinsulin like growth factor binding protein 3
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Synonyms gene name
- insulin-like growth factor binding protein 3
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Synonyms
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Synonyms name
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Locus
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Discovery year1991-07-09
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Insulin like growth factor binding proteins
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameRNA, U6 small nuclear 53, pseudogene
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Synonyms gene
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Synonyms gene name
- RNA, U6 small nuclear 53
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Locus
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Discovery year2011-08-08
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Entrez gene record
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RefSeq identity
Gene info
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Identity
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Gene
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Long gene namesmall nucleolar RNA, C/D box 8
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Synonyms gene
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Synonyms gene name
- RNA, U6C small nucleolar
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Synonyms
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GenBank acession
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Locus
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Discovery year2003-01-13
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Small nucleolar RNAs, C/D box
Gene info
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Identity
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Gene
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Long gene nameRB binding protein 4, chromatin remodeling factor
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Synonyms gene name
- retinoblastoma-binding protein 4
- retinoblastoma binding protein 4
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Synonyms
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GenBank acession
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Locus
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Discovery year1995-05-05
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- EMSY complex
- SIN3 histone deacetylase complex subunits
- WD repeat domain containing
- NuRD complex subunits
- Polycomb repressive complex 2
- NURF complex
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameintraflagellar transport 52
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Synonyms gene
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Synonyms gene name
- chromosome 20 open reading frame 9
- intraflagellar transport 52 homolog (Chlamydomonas)
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Synonyms
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GenBank acession
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Locus
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Discovery year2001-06-21
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- IFT-B1 complex
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namelectin, mannose binding 1
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Synonyms gene
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Synonyms gene name
- coagulation factor V-factor VIII combined deficiency
- lectin, mannose-binding, 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1996-06-06
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data