Rat CD8α Mouse Monoclonal Antibody [53-6.72]-PURE

• Catalog number
  BD-MO8APU(V500)
• Price
  Please ask
• Size
  0,5 mg

• Description
  Rat CD8α Mouse Monoclonal Antibody [53-6.72]-PURE is a mouse monoclonala antibody, specific for [53-6.72] clones, this product was conjugated with PURE format and reported for use in flow cytometric analysis to react with CD8 α proteins in thymocytes, T cell subset, some NK cells, lymphoid dendritic cells, Most thymocytes, CD8 α acts as a co-TCR recptor to activate T cells, also regulate the efficience of cell-cell interactions.
• Other antibodies
• Clone
  53-6.72
• Conjugate
  PURE
• Gene Name
  CD8 α
• Other Names of gene
  T8, Lyt2, Ly-2
• Concentration
  500 µg/mL
• Application
  Flow Cytometry Method
• Immunogen
  Mouse thymocytes/splenocytes
• Formulation
  Aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium azide (NaN3).
• Storage
  2-8°C, store in dark, do not freeze
• Expiration
  After 1 year
• Remark
  For Recherche Use Only.
• Properties
  If you buy Antibodies supplied by Immunostep they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes. Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus, Rattus norvegicus
• Additional description
  The ultrapure CD8α Mouse Monoclonal Antibody [53-6 72]-PURE supplied from Immunostep is supplied in 1. The reagent contains very low traces of production synthesis impurities and is highly purified by ultra filtration and distillation for the chemical compounds.
• French translation
  anticorps

• Gene target
  CD8α   Monoclonal   [53-6   72]  
• Gene symbol
  CD8A, IGLVIV-53, IGHV3-53, IGHVII-53-1, IGFBP3, RNU6-53P, SNORD8, RBBP4, IFT52, LMAN1
• Short name
  CD8α Mouse Monoclonal Antibody [53-6 72]-PURE
• Technique
  Mouse monoclonal, Antibody, Mouse, Pure, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies, mouses, mouse monoclonals, pure products
• Host
  Rat, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
• Isotype
  Rat IgG2b
• Species
  Mouses, Rats
• Alternative name
  Rat Anti Mouse CD8 α Antibody-PURE
• Alternative technique
  antibodies, murine, purified

Gene info

• Identity
  HGNC:1706
• Gene
  CD8A
• Long gene name
  CD8a molecule
• Synonyms gene
  • CD8
• Synonyms gene name
  • CD8 antigen, alpha polypeptide (p32)
  • T-cell surface glycoprotein CD8 alpha chain
• Locus
  2p11.2
• Discovery year
  1986-01-01
• Entrez gene record
  925
• Pubmed identfication
  • 1541829
• RefSeq identity
  • NM_001768
• Classification
  • V-set domain containing
  • CD molecules
• VEGA ID
  OTTHUMG00000130265
• Locus Specific Databases
  • CD8Abase: Mutation registry for CD8 deficiency
  • LRG_44

Gene info

• Identity
  HGNC:5941
• Gene
  IGLVIV-53
• Long gene name
  immunoglobulin lambda variable (IV)-53 (pseudogene)
• Synonyms gene name
  • immunoglobulin lambda variable (IV)-53
  • immunoglobulin lambda variable (IV)-53 pseudogene
• Synonyms
  • IGLV(IV)-53
• GenBank acession
  • D86996
• Locus
  22q11.22
• Discovery year
  2000-05-08
• Entrez gene record
  28762
• RefSeq identity
  • NG_000002
• Classification
  • Immunoglobulin lambda locus at 22q11.2
• VEGA ID
  OTTHUMG00000151585

Gene info

• Identity
  HGNC:5610
• Gene
  IGHV3-53
• Long gene name
  immunoglobulin heavy variable 3-53
• GenBank acession
  • M99679
• Locus
  14q32.33
• Discovery year
  2000-04-04
• Entrez gene record
  28420
• RefSeq identity
  • NG_001019
• Classification
  • Immunoglobulin heavy locus at 14q32.33
• VEGA ID
  OTTHUMG00000151966

Gene info

• Identity
  HGNC:5685
• Gene
  IGHVII-53-1
• Long gene name
  immunoglobulin heavy variable (II)-53-1 (pseudogene)
• Synonyms gene name
  • immunoglobulin heavy variable (II)-53-1
  • immunoglobulin heavy variable (II)-53-1 pseudogene
• Synonyms
  • IGHV(II)-53-1
• GenBank acession
  • AB019438
• Locus
  14q32.33
• Discovery year
  2000-04-17
• Entrez gene record
  28362
• RefSeq identity
  • NG_001019
• Classification
  • Immunoglobulin heavy locus at 14q32.33
• VEGA ID
  OTTHUMG00000151954

Gene info

• Identity
  HGNC:5472
• Gene
  IGFBP3
• Long gene name
  insulin like growth factor binding protein 3
• Synonyms gene name
  • insulin-like growth factor binding protein 3
• Synonyms
  • IBP3
  • BP-53
• Synonyms name
  • growth hormone-dependent binding protein
  • acid stable subunit of the 140 K IGF complex
  • binding protein 53
  • binding protein 29
  • IGF-binding protein 3
• Locus
  7p12.3
• Discovery year
  1991-07-09
• Entrez gene record
  3486
• Pubmed identfication
  • 1695633
• RefSeq identity
  • NM_001013398
• Classification
  • Insulin like growth factor binding proteins
• VEGA ID
  OTTHUMG00000023769
• Locus Specific Databases
  • LRG_68

Gene info

• Identity
  HGNC:42543
• Gene
  RNU6-53P
• Long gene name
  RNA, U6 small nuclear 53, pseudogene
• Synonyms gene
  • RNU6-53
• Synonyms gene name
  • RNA, U6 small nuclear 53
• Locus
  13q12.3
• Discovery year
  2011-08-08
• Entrez gene record
  100873762
• RefSeq identity
  • NR_046928

Gene info

• Identity
  HGNC:20159
• Gene
  SNORD8
• Long gene name
  small nucleolar RNA, C/D box 8
• Synonyms gene
  • RNU6C
• Synonyms gene name
  • RNA, U6C small nucleolar
• Synonyms
  • mgU6-53
• GenBank acession
  • AJ243222
• Locus
  14q11.2
• Discovery year
  2003-01-13
• Entrez gene record
  319103
• Pubmed identfication
  • 10490628
• RefSeq identity
  • NR_002916
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:9887
• Gene
  RBBP4
• Long gene name
  RB binding protein 4, chromatin remodeling factor
• Synonyms gene name
  • retinoblastoma-binding protein 4
  • retinoblastoma binding protein 4
• Synonyms
  • RbAp48
  • NURF55
  • lin-53
• GenBank acession
  • BC053904
• Locus
  1p35.1
• Discovery year
  1995-05-05
• Entrez gene record
  5928
• Pubmed identfication
  • 8350924
  • 14609955
  • 17531812
• RefSeq identity
  • NM_005610
• Classification
  • EMSY complex
  • SIN3 histone deacetylase complex subunits
  • WD repeat domain containing
  • NuRD complex subunits
  • Polycomb repressive complex 2
  • NURF complex
• VEGA ID
  OTTHUMG00000007998

Gene info

• Identity
  HGNC:15901
• Gene
  IFT52
• Long gene name
  intraflagellar transport 52
• Synonyms gene
  • C20orf9
• Synonyms gene name
  • chromosome 20 open reading frame 9
  • intraflagellar transport 52 homolog (Chlamydomonas)
• Synonyms
  • CGI-53
  • NGD5
  • dJ1028D15.1
  • NGD2
• GenBank acession
  • AF151811
• Locus
  20q13.12
• Discovery year
  2001-06-21
• Entrez gene record
  51098
• Pubmed identfication
  • 10810093
• RefSeq identity
  • NM_016004
• Classification
  • IFT-B1 complex
• VEGA ID
  OTTHUMG00000032513

Gene info

• Identity
  HGNC:6631
• Gene
  LMAN1
• Long gene name
  lectin, mannose binding 1
• Synonyms gene
  • F5F8D
• Synonyms gene name
  • coagulation factor V-factor VIII combined deficiency
  • lectin, mannose-binding, 1
• Synonyms
  • MR60
  • ERGIC-53
  • ERGIC53
  • gp58
  • MCFD1
  • FMFD1
• Synonyms name
  • endoplasmic reticulum-golgi intermediate compartment protein 53
• GenBank acession
  • X71661
• Locus
  18q21.32
• Discovery year
  1996-06-06
• Entrez gene record
  3998
• Pubmed identfication
  • 9546392
  • 8854877
• RefSeq identity
  • NM_005570
• VEGA ID
  OTTHUMG00000132758
• Locus Specific Databases
  • LRG_595

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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