Rat Anti Mouse CD8 α Antibody-Biotin

• Catalog number
  MO8AB(V100)
• Price
  Please ask
• Size
  0,1 mg

• Description
  Rat Anti Mouse CD8 α Antibody-Biotin is a mouse monoclonala antibody, specific for [53-6.72] clones, this product was conjugated with Biotin format and reported for use in flow cytometric analysis to react with CD8 α proteins in thymocytes, T cell subset, some NK cells, lymphoid dendritic cells, Most thymocytes, CD8 α acts as a co-TCR recptor to activate T cells, also regulate the efficience of cell-cell interactions.
• Other rodent antibodies
• Clone
  53-6.72
• Conjugate
  Biotin
• Gene Name
  CD8 α
• Other Names of gene
  T8, Lyt2, Ly-13
• Concentration
  500 µg/mL
• Application
  Flow Cytometry Method
• Immunogen
  Mouse thymocytes/splenocytes
• Formulation
  Aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium azide (NaN3).
• Storage
  2-8°C, store in dark, do not freeze
• Expiration
  After 1 year
• Remark
  For Recherche Use Only.
• Additional description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. This is against a protein of mus musculus directed antibody. Cytotoxic T cells cluster differentiators for flow cytometry. This transmembrane glycoprotein is detected by monoclonals and has a lot of clones available with different affinity.
• Properties
  If you buy Antibodies supplied by Immunostep they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.
• Conjugation
  Biotinylated
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus, Rattus norvegicus
• About
  Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
• French translation
  anticorps

• Gene target
  CD8  
• Gene symbol
  CD8A
• Short name
  Anti Mouse CD8 α Antibody-
• Technique
  anti mouse, Antibody, Mouse, anti, antibody to, anti mouse antibodies, antibodies against human proteins, antibodies for, mouses
• Host
  Rat
• Isotype
  Rat IgG2b
• Label
  Biotin
• Species
  Mouses, Rats
• Alternative name
  Rat CD8α Mouse Monoclonal Antibody [53-6.72]-Biotin
• Alternative technique
  antibodies, murine

Gene info

• Identity
  HGNC:1706
• Gene
  CD8A
• Long gene name
  CD8a molecule
• Synonyms gene
  • CD8
• Synonyms gene name
  • CD8 antigen, alpha polypeptide (p32)
  • T-cell surface glycoprotein CD8 alpha chain
• Locus
  2p11.2
• Discovery year
  1986-01-01
• Entrez gene record
  925
• Pubmed identfication
  • 1541829
• RefSeq identity
  • NM_001768
• Classification
  • V-set domain containing
  • CD molecules
• VEGA ID
  OTTHUMG00000130265
• Locus Specific Databases
  • CD8Abase: Mutation registry for CD8 deficiency
  • LRG_44

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