Thyroid Hormone Receptor Alpha (TR Alpha/NR1A1) (THRA), Human

  • Catalog number
    GWB-8472E0
  • Price
    Please ask
  • Size
    1 vial
  • Old catalog number
    18-251-405305
  • Storage temperature
    store cold
  • Expiry date
    1 y
  • Category
    research antibodies, ELISAs, recombinant proteins, vectors and reagents for laboratory use
  • Description
    The Thyroid Hormone Receptor Alpha (TR Alpha/NR1A1) (THRA), is a α- or alpha protein sometimes glycoprotein present in blood. Hormone releasing factors and releasing hormones are  signaling molecules produced by glands in multicellular organisms. The glands that secrete Luteinizing hormones LHRG and LH, FSH comprise the endocrine signaling system. The term growth hormone releasing hormone GHRH is sometimes extended to include chemicals produced by cells that affect the same cell (autocrine or intracrine signaling) or nearby cells (paracrine signaling). Human recombinant LHRG and GHRH are produced in E. coli or in yeast cells. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
  • Properties
    Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
  • Gene target
  • Short name
    Thyroid Hormone Receptor Alpha (TR Alpha/NR1A1) (THRA),
  • Species
    Human, Humans
  • Alternative name
    Thyroid Hormone Receptor a (TR a/NR1A1) (thyroid hormone receptor, alpha), H. sapiens
  • Alternative to gene target
    thyroid hormone receptor, alpha, AR7 and c-ERBA-1 and CHNG6 and EAR7 and ERB-T-1 and ERBA and ERBA1 and NR1A1 and THRA1 and THRA2, THRA and IDBG-47063 and ENSG00000126351 and 7067, thyroid hormone binding, nuclei, Thra and IDBG-210748 and ENSMUSG00000058756 and 21833, THRA and IDBG-639592 and ENSBTAG00000010745 and 532621
  • Tissue
    thyroid
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