Thyroid hormone receptor alpha Antibody / THRA
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Catalog number
F53935-0.05ML
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Price
Please ask
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Size
0.05 ml
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Category
Antibody
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Concentration
In 1X PBS, pH 7.4, with 0.09% sodium azide
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Form
Antigen affinity purified
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Conjugation
Unconjugated
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Clone
Polyclonal antibody
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Recognised antigen
Thyroid hormone receptor alpha / THRA
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Host animal
Rabbit (Oryctolagus cuniculus)
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Clonality
Polyclonal (rabbit origin)
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Species reactivity
Human (Homo sapiens), Mouse (Mus musculus), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
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Tested applications
WB
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Recommended dilutions
Western blot: 1:1000-2000
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Intented use
This Thyroid hormone receptor alpha antibodyis to be used only for research purposes and not for diagnostics..
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Gene ID
7067
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Uniprot
P10827
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Purity
Antigen affinity
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Description
Thyroid hormone receptor alpha (THRA) is a nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine.
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Immunogen
A portion of amino acids 107-139 from the human protein was used as the immunogen for the Thyroid hormone receptor alpha antibody.
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Storage
Aliquot the Thyroid hormone receptor alpha antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
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Additional description
The Anti- Thyroid hormone receptor alpha / THRA is a α- or alpha protein sometimes glycoprotein present in blood. Hormone releasing factors and releasing hormones are signaling molecules produced by glands in multicellular organisms. The glands that secrete Luteinizing hormones LHRG and LH, FSH comprise the endocrine signaling system. The term growth hormone releasing hormone GHRH is sometimes extended to include chemicals produced by cells that affect the same cell (autocrine or intracrine signaling) or nearby cells (paracrine signaling). Human recombinant LHRG and GHRH are produced in E. coli or in yeast cells. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Properties
If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
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Gene target
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Gene symbol
THRA
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Short name
Anti- Thyroid hormone receptor alpha / THRA
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Technique
Antibody, antibodies against human proteins, antibodies for
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Isotype
Rabbit Ig
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Alternative name
Antibodies to Thyroid hormone receptor alpha / THRA
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Alternative technique
antibodies
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Alternative to gene target
thyroid hormone receptor, alpha, AR7 and c-ERBA-1 and CHNG6 and EAR7 and ERB-T-1 and ERBA and ERBA1 and NR1A1 and THRA1 and THRA2, THRA and IDBG-47063 and ENSG00000126351 and 7067, thyroid hormone binding, nuclei, Thra and IDBG-210748 and ENSMUSG00000058756 and 21833, THRA and IDBG-639592 and ENSBTAG00000010745 and 532621
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Tissue
thyroid
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Gene info
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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