Plasminogen Activator Inhibitor 1 (PAI-1)
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Catalog number
GWB-3EE14F
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Price
Please ask
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Size
1 x 1 vial
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Old catalog number
06-271-83423
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Storage temperature
store cold
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Expiry date
1 y
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Category
research antibodies, ELISAs, recombinant proteins, vectors and reagents for laboratory use
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Description
Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.
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Gene
Plasminogen activator inhibitor-1 (PAI-1) also known as endothelial plasminogen activator inhibitor or serpin E1 is a protein that in humans is encoded by the SERPINE1 gene. Elevated PAI-1 is a risk factor for thrombosis and atherosclerosis
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Gene target
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Gene symbol
SERPINE1, SERPINB2, SERBP1
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Short name
Plasminogen Activator Inhibitor 1 (PAI-1)
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Alternative name
Plasminogen Activator suppressor 1 (PAI-1)
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Gene info
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Identity
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Gene
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Long gene name
serpin family E member 1
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Synonyms gene
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Synonyms gene name
- serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
1986-01-01
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Serpin peptidase inhibitors
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene name
serpin family B member 2
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Synonyms gene
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Synonyms gene name
- serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 2
- serpin peptidase inhibitor, clade B (ovalbumin), member 2
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
1989-02-07
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Serpin peptidase inhibitors
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VEGA ID
Gene info
Product images
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