Human IgE

  • Catalog number
    31R-1089
  • Price
    Please ask
  • Size
    1 mg
  • Category
    Immunoglobulins
  • Antibody Subtype
    Purified Immunoglobulins
  • Area of research
    Immunology
  • Reactivity
    Human
  • Type of protein
    Native
  • Expression System
    Cell culture
  • Grade Purity
    Partially pure
  • Source
    Cell Culture
  • Concentration
    6-7 mg/ml
  • Form Buffer
    Provided as liquid in 0.1M Tris, 0.2M NaCl at pH 7.5
  • Storage
    Store at 4 deg C for short term. Aliquot and store at -20 deg C for longer terms. Avoid freeze thaw cycles.
  • Shipping conditions
    Blue Ice
  • Tested for
    Control
  • URL
  • Properties
    Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples. Immunoglobulin E (IgE) kappa or Fc specific antibody is a kind of antibody (or immunoglobulin (Ig) "isotype") that has only been found in mammals. IgE is synthesized by plasma cells. Monomers of IgE consist of two heavy chains (ε chain) and two light chains, with the ε chain containing 4 Ig-like constant domains (Cε1-Cε4). IgEs play a role in allergy and response to parasite infection. High levels of IgEs caused by parasites can lower the allergic reaction of patients to allergens common present in the human environment. As such the parasite history of an allergic patient needs to be taken in consideration as a positive factor.
  • Short name
    IgE
  • Technique
    IgE, IgEs
  • Isotype
    IgE, IgE
  • Species
    Human, Humans
  • Alternative name
    Purified Native Human IgE
  • Alternative technique
    immunoglobulin-e
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