Trypsin inhibitor

Category

Biological Reagents
Antibody Subtype

Enzymes
Area of research

Proteases, Inhibitors, & Enzymes
Source

Soybean
Form Buffer

Provided in lyophilized form. Dissolves readily at 5mg/ml in 0.067M Potassium phosphate buffer, pH 7.6 to give a clear solution
Storage

Store at -15 deg C or below
Shipping conditions

Blue Ice
Bioactivity

7000 BAEE U/mg material
URL
More info
Description

Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.

Identity

HGNC:11245
Gene

SPINK2
Long gene name

serine peptidase inhibitor Kazal type 2
Synonyms gene name
- serine protease inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
Synonyms
- HUSI-II
Synonyms name
- acrosin-trypsin inhibitor
GenBank acession
- BC022514
Locus

4q12
Discovery year

1993-12-01
Entrez gene record

6691
Pubmed identfication
- 8428671
RefSeq identity
- NM_021114
Classification
- Serine peptidase inhibitors, Kazal type
VEGA ID

OTTHUMG00000128769

Identity

HGNC:21449
Gene

ITIH5
Long gene name

inter-alpha-trypsin inhibitor heavy chain 5
Synonyms gene name
- inter-alpha (globulin) inhibitor H5
- inter-alpha-trypsin inhibitor heavy chain family, member 5
Synonyms
- MGC10848
Locus

10p14
Discovery year

2004-01-28
Entrez gene record

80760
Pubmed identfication
- 14744536
RefSeq identity
- NM_030569
Classification
- Inter-alpha-trypsin inhibitor heavy chains
VEGA ID

OTTHUMG00000017635

Identity

HGNC:28907
Gene

ITIH6
Long gene name

inter-alpha-trypsin inhibitor heavy chain family member 6
Synonyms gene
- ITIH5L
Synonyms gene name
- inter-alpha (globulin) inhibitor H5-like
- inter-alpha-trypsin inhibitor heavy chain family, member 6
Synonyms
- UNQ6369
GenBank acession
- AY358170
Locus

Xp11.22
Discovery year

2004-08-16
Entrez gene record

347365
Pubmed identfication
- 12975309
RefSeq identity
- NM_198510
Classification
- Inter-alpha-trypsin inhibitor heavy chains
VEGA ID

OTTHUMG00000021634
Locus Specific Databases
- Global Variome shared LOVD