IL8 protein

Category

Proteins
Antibody Subtype

Recombinant Proteins
Area of research

Cytokines & Growth Factors
Reactivity

Human
Type of protein

Recombinant
Expression System

Escherichia coli
Grade Purity

Grater than 98% pure
Method of Purification

IL8 protein was purified using a a proprietary chromatographic technique.
Form Buffer

Provided as a sterile filtered and lyophilized from a solution containing 20 mM PBS, pH 7.4, and 50 mM NaCl
Storage

Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Shipping conditions

Blue Ice
Bioactivity

The ED50 as determined by its chemotaxis of hCXCR2 transfected mouse BaF/3 cells is less than 0.05 ng/ml, corresponding to a specific activity of 20 x 10^6 units/mg
URL
More info
Gene

Interleukin 8 (IL8 or chemokine (C-X-C motif) ligand 8, CXCL8) is a chemokine produced by macrophages and other cell types such as epithelial cells, airway smooth muscle cells and endothelial cells. Endothelial cells store IL-8 in their storage vesicles, the Weibel-Palade bodies. In humans, the interleukin-8 proteins encoded by the IL8 gene. IL-8 is initially produced as a precursor peptide of 99 amino acids long which then undergoes cleavage to create several active IL-8 isoforms. In culture, a 72 amino acid peptide is the major form secreted by macrophages. Recombinant, rec. E. coli interleukin-8 for cell culture or antibody production.

Gene target

IL8 protein
Gene symbol

CXCL8
Short name

IL8 protein
Alternative name

Purified recombinant Human IL8 protein
Alternative to gene target

interleukin 8, GCP-1 and GCP1 and IL8 and LECT and LUCT and LYNAP and MDNCF and MONAP and NAF and NAP-1 and NAP1, IL8 and IDBG-23954 and ENSG00000169429 and 3576, chemokine activity, Extracellular, IL8 and IDBG-643010 and ENSBTAG00000019716 and 280828