IL8 protein

• Catalog number
  30R-2166
• Price
  Please ask
• Size
  10 µg

• Category
  Proteins
• Antibody Subtype
  Recombinant Proteins
• Area of research
  Cytokines & Growth Factors
• Specificity
  Human
• Reactivity
  Human
• Type of protein
  Recombinant
• Expression System
  Escherichia coli
• Grade Purity
  Grater than 98% pure
• Method of Purification
  IL8 protein was purified by affinity chromatography.
• Concentration
  500 ug/ml
• Form Buffer
  Provided as a sterile liquid with phosphate buffered saline, pH 7.2,1.0% BSA. 0.22 um filtered.
• Storage
  Store at -70 deg C or less.
• Shipping conditions
  Blue Ice
• Tested for
  WB
• Usage Recommendations
  WB: 5 ug/ml
• Bioactivity
  Measured by chemotaxis assay of human peripheral blood neutrophils. Maximal chemoattractant activity was observed between 10-100 ng/ml.
• Assay Information
  This 4F3‐3C8‐2B7 antibody has been tested by western blot analysis of transfected cells. Titration of the antibody from 5 ug/ml is recommended
• URL
• More info
• Gene
  Interleukin 8 (IL8 or chemokine (C-X-C motif) ligand 8, CXCL8) is a chemokine produced by macrophages and other cell types such as epithelial cells, airway smooth muscle cells and endothelial cells. Endothelial cells store IL-8 in their storage vesicles, the Weibel-Palade bodies. In humans, the interleukin-8 proteins encoded by the IL8 gene. IL-8 is initially produced as a precursor peptide of 99 amino acids long which then undergoes cleavage to create several active IL-8 isoforms. In culture, a 72 amino acid peptide is the major form secreted by macrophages. Recombinant, rec. E. coli interleukin-8 for cell culture or antibody production.

• Gene target
  IL8   protein  
• Gene symbol
  CXCL8
• Short name
  IL8 protein
• Alternative name
  Purified recombinant Human IL8 protein
• Alternative to gene target
  interleukin 8, GCP-1 and GCP1 and IL8 and LECT and LUCT and LYNAP and MDNCF and MONAP and NAF and NAP-1 and NAP1, IL8 and IDBG-23954 and ENSG00000169429 and 3576, chemokine activity, Extracellular, IL8 and IDBG-643010 and ENSBTAG00000019716 and 280828

Gene info

• Identity
  HGNC:6025
• Gene
  CXCL8
• Long gene name
  C-X-C motif chemokine ligand 8
• Synonyms gene
  • IL8
• Synonyms gene name
  • interleukin 8
  • chemokine (C-X-C motif) ligand 8
• Synonyms
  • SCYB8
  • LUCT
  • LECT
  • MDNCF
  • TSG-1
  • IL-8
  • NAP-1
  • 3-10C
  • MONAP
  • AMCF-I
  • LYNAP
  • NAF
  • b-ENAP
  • GCP-1
  • K60
  • GCP1
  • NAP1
• Synonyms name
  • neutrophil-activating peptide 1
  • granulocyte chemotactic protein 1
  • monocyte-derived neutrophil chemotactic factor
  • lung giant cell carcinoma-derived chemotactic protein
  • tumor necrosis factor-induced gene 1
  • monocyte-derived neutrophil-activating peptide
  • lymphocyte derived neutrophil activating peptide
  • beta endothelial cell-derived neutrophil activating peptide
  • alveolar macrophage chemotactic factor I
• GenBank acession
  • Y00787
• Locus
  4q13.3
• Discovery year
  1989-06-30
• Entrez gene record
  3576
• Pubmed identfication
  • 1427896
  • 11178128
• RefSeq identity
  • NM_000584
• Classification
  • Chemokine ligands
  • Interleukins
• VEGA ID
  OTTHUMG00000151316

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