IgM Isotype Control Fc fusion protein

Research Area

Immunology
Product Subtype

Isotype Controls
Product Type

Biological Reagents
Concentration

500 ug/ml
Form and Buffer

aqueous buffer with 0.09% sodium azide, may contain carrier protein/stabilizer.
Storage

Store at 2-8 deg C. Do not freeze. Protect from light.
Shipping Info

Blue Ice
Applications

FC
Description

Isotype or positive controls by peptides, antibodies and deactivated samples. Fusion proteins or chimeric proteins are proteins created through the joining of two or more genes that originally coded for separate proteins. A GFP gene is often used as tag to a reporter gene. Fusion lentiverctors can be used as viral particles to produce proteins that carry for example a GFP tag. Antigen purification of recombinant fusion tag proteins is a frequent strategy using a Fralg tag.
Properties

Immunoglobulin M, or IgM for short, is a basic antibody that is produced by B cells. IgM is by far the physically largest antibody in the human circulatory system. It is the first antibody to appear in response to initial exposure to an antigen, Immunoglobulin Isotype specific antibodies and controls are specific to the immunoglobulin heavy chains and immunoglobulin light chains. Mouse monoclonal antibodies from this clone have all the same affinity to the antigen. Also polyclonal antibodies are Isotype purified amd conjugated or if they are used as control non conjugated.
Group

isotypes

Identity

HGNC:14875
Gene

FCRL2
Long gene name

Fc receptor like 2
Synonyms gene
- SPAP1
Synonyms gene name
- SH2 domain-containing phosphatase anchor protein 1
- Fc receptor-like 2
Synonyms
- FCRH2
- IRTA4
- CD307b
GenBank acession
- AF319438
Locus

1q23.1
Discovery year

2001-04-06
Entrez gene record

79368
Pubmed identfication
- 11162587
RefSeq identity
- NM_030764
Classification
- CD molecules
- Immunoglobulin like domain containing
VEGA ID

OTTHUMG00000019399