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Long name
Mouse Monoclonal Antibody against Human IgM, Clone: CH2
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Antigen
IgM
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Species reactivity
Human (Homo sapiens)
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Negative species reactivity
at the time of upload there has been no data, please, contact us to obtain most recent information on species reactivity and cross reactivity
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Clonality
Monoclonal Antibody (Mab)
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Clone
CH2
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Applications
WB, FC, ICC, ELISA
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Immunogen
Purified human IgM.
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Format conjugation
Peroxidase
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Specificity
The antibody CH2 reacts with Fc fragment of human IgM.
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Research area
Immunoglobulins (Human)
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Concentration
1 mg/ml
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Storage buffer
The reagent is provided in stabilizing phosphate buffered saline (PBS) solution containing 0.01% (w/v) thimerosal.
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Shipping and storage
Mouse Monoclonal Antibody against Human IgM, Clone: CH2 is transported on blue ice/ice packs and should be stored at temperatures between 1 and 5 degrees Celsius. Do not freeze! Avoid exposing the product to direct light, especially the conjugated antibodies as most conjugates are very sentitive to light.
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Background
Immunoglobulin M (IgM) is produced as a 900 kDa pentamer, which is an efficient complement binder. This antibody type is produced initially in the immune response and it is the first immunoglobulin class to be synthesized by a fetus or newborn. IgM antibodies do not cross the placenta. IgM concentration in blood is 0.12 g/l and its biological survival (plasma T1/2) is 5 days.
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Purity
> 95% (by SDS-PAGE)
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Purification method
Purified by affinity chromatography
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References
Contact us for the most recent list of references
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Properties
If you buy Antibodies supplied by Exbio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Immunoglobulin M, or IgM for short, is a basic antibody that is produced by B cells. IgM is by far the physically largest antibody in the human circulatory system. It is the first antibody to appear in response to initial exposure to an antigen
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About
Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
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French translation
anticorps