gentaur logogentaur logo
x

Human IgM (13A11) Monoclonal Antibody

  • Catalog number
    bsm-50221M
  • Product name
    Human IgM (13A11) Monoclonal Antibody
  • Size
    0.1ml
  • Short name
    Anti-Human IgM
  • Long name
    Human IgM (13A11) Monoclonal Antibody
  • Also known as
    Human IgM (13A11) Monoclonal Antibody
  • Category
    Primary Antibodies
  • Conjugation
    Unconjugated
  • Host
    Mouse (Mus musculus)
  • Target Antigen
    Human IgM
  • Specificity
    This is a highly specific antibody against Human IgM.
  • Modification s
    None
  • Modification site s
    Unmodified antibody
  • Clonality
    Monoclonal
  • Clone number
    13A11
  • Isotype
    Immunoglobulin G (IgG)1 λ, IgM
  • Concentration
    1ug per 1ul
  • Source
    Protein purified from Human plasma
  • Swiss Prot
    P01871
  • Tested Applications
    WB, IHC-P, IP
  • Recommended dilutions
    WB (0.5 ug/mL) IP (2.0 ug) IHC-P
  • Cross reactivity
    Human
  • Cross reactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Background of the target antigen
    Immunoglobulin M (IgM) forms polymers where multiple immunoglobulins are covalently linked together with disulfide bonds, normally as a pentamer and the J chain is attached to most pentamers. It has a large molecular mass of approximately 900 kD. Due to its polymeric nature, IgM possesses high avidity, and is particularly effective at complement activation. It is sometimes called a "natural antibody", but it is likely that the antibodies arise due to sensitization in the very young to antigens that are naturally occurring in nature. IgM is the first immunoglobulin expressed by mature B cells. IgM antibodies appear early in the course of an infection and usually do not reappear after further exposure. IgM antibodies do not pass across the human placenta. These two biological properties of IgM make it useful in the diagnosis of infectious diseases. Demonstrating IgM antibodies in patients serum indicates recent or in serum from a neonate intrauterine infection such as congenital rubella.
  • Purification method
    Purified by Protein G.
  • Storage conditions
    Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
  • Gene target
    13A11 Monoclonal
  • isotype filter
    • Immunoglobulin G IgG 1 λ
  • technique filter
    • Antibody
    • IgM
  • Technique
    Antibody, IgM, antibodies against human proteins, antibodies for, IgMs, Monoclonals or monoclonal antibodies
  • Alternative technique
    antibodies, immunoglobulin-m