ABRA1 monoclonal antibody
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Catalog number11-619-C100
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Price:
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Size100ug
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Long nameMouse Monoclonal Antibody against Human ABRA1, Clone: ABRA1-01
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AntigenABRA1
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Species reactivityHuman (Homo sapiens), Other not tested
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Negative species reactivityat the time of upload there has been no data, please, contact us to obtain most recent information on species reactivity and cross reactivity
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ClonalityMonoclonal Antibody (Mab)
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CloneABRA1-01
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ApplicationsFC, IP, WB
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ImmunogenRecombinant protein corresponding to amino acids 1-313 of ABRA1 with N-terminal His6 tag_x000D_
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Format conjugationpurified; unconjugated
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SpecificityThe mouse monoclonal antibody ABRA1-01 recognizes N-terminal part of ABRA1 (Abraxas, CCDC98), an adaptor protein involved in DNA repair, which migrates as a 45 kDa band on PAAGE under reducing conditions. _x000D_
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Research areaAdaptor Proteins (Human), Transcription Regulation & Nuclear Proteins (Human)
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Concentration1 mg/ml
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Storage bufferPhosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
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Shipping and storageMouse Monoclonal Antibody against Human ABRA1, Clone: ABRA1-01 is transported on blue ice/ice packs and should be stored at temperatures between 1 and 5 degrees Celsius. Do not freeze! Avoid exposing the product to direct light, especially the conjugated antibodies as most conjugates are very sentitive to light.
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BackgroundABRA1 (Abraxas), also known as CCDC98, is an adaptor protein that is essential for formation and function of BRCA1 A tumor suppressor complex. This complex plays critical roles in DNA repair, cell cycle checkpoint control, and maintenance of genomic stability. ABRA1 mediates interaction of ubiquitin-interacting motif-containing protein RAP80 and deubiquitination enzyme BRCC36 with BRCA1/BARD1. ABRA1 controls both DNA-damage-induced formation of BRCA1 foci and BRCA1-dependent G2/M checkpoint activation._x000D_
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Purity> 95% (by SDS-PAGE)
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Purification methodPurified by protein-A affinity chromatography
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ReferencesContact us for the most recent list of references
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PropertiesIf you buy Antibodies supplied by Exbio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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AboutMonoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
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French translationanticorps
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Gene target
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Gene symbolABRAXAS1
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Short nameAnti-ABRA1 Mab
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TechniqueAntibody, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies
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HostMouse (Mus musculus)
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IsotypeIgG
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Alternative nameMouse Monoclonal to ABRA1
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameabraxas 1, BRCA1 A complex subunit
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Synonyms gene
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Synonyms gene name
- coiled-coil domain containing 98
- family with sequence similarity 175, member A
- family with sequence similarity 175 member A
- Abraxas 1, BRCA1 A complex subunit
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2006-04-03
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- BRCA1 A complex
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data