ABRA1 monoclonal antibody

• Catalog number
  11-619-C100
• Price
  Please ask
• Size
  100ug

• Long name
  Mouse Monoclonal Antibody against Human ABRA1, Clone: ABRA1-01
• Antigen
  ABRA1
• Species reactivity
  Human (Homo sapiens), Other not tested
• Negative species reactivity
  at the time of upload there has been no data, please, contact us to obtain most recent information on species reactivity and cross reactivity
• Clonality
  Monoclonal Antibody (Mab)
• Clone
  ABRA1-01
• Applications
  FC, IP, WB
• Immunogen
  Recombinant protein corresponding to amino acids 1-313 of ABRA1 with N-terminal His6 tag_x000D_
• Format conjugation
  purified; unconjugated
• Specificity
  The mouse monoclonal antibody ABRA1-01 recognizes N-terminal part of ABRA1 (Abraxas, CCDC98), an adaptor protein involved in DNA repair, which migrates as a 45 kDa band on PAAGE under reducing conditions. _x000D_
• Research area
  Adaptor Proteins (Human), Transcription Regulation & Nuclear Proteins (Human)
• Concentration
  1 mg/ml
• Storage buffer
  Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
• Shipping and storage
  Mouse Monoclonal Antibody against Human ABRA1, Clone: ABRA1-01 is transported on blue ice/ice packs and should be stored at temperatures between 1 and 5 degrees Celsius. Do not freeze! Avoid exposing the product to direct light, especially the conjugated antibodies as most conjugates are very sentitive to light.
• Background
  ABRA1 (Abraxas), also known as CCDC98, is an adaptor protein that is essential for formation and function of BRCA1 A tumor suppressor complex. This complex plays critical roles in DNA repair, cell cycle checkpoint control, and maintenance of genomic stability. ABRA1 mediates interaction of ubiquitin-interacting motif-containing protein RAP80 and deubiquitination enzyme BRCC36 with BRCA1/BARD1. ABRA1 controls both DNA-damage-induced formation of BRCA1 foci and BRCA1-dependent G2/M checkpoint activation._x000D_
• Purity
  > 95% (by SDS-PAGE)
• Purification method
  Purified by protein-A affinity chromatography
• Datasheet
• References
  Contact us for the most recent list of references
• Properties
  If you buy Antibodies supplied by Exbio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
• French translation
  anticorps

• Gene target
  ABRA1   monoclonal  
• Gene symbol
  ABRAXAS1
• Short name
  Anti-ABRA1 Mab
• Technique
  Antibody, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies
• Host
  Mouse (Mus musculus)
• Isotype
  IgG
• Alternative name
  Mouse Monoclonal to ABRA1
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:25829
• Gene
  ABRAXAS1
• Long gene name
  abraxas 1, BRCA1 A complex subunit
• Synonyms gene
  • CCDC98
  • FAM175A
• Synonyms gene name
  • coiled-coil domain containing 98
  • family with sequence similarity 175, member A
  • family with sequence similarity 175 member A
  • Abraxas 1, BRCA1 A complex subunit
• Synonyms
  • FLJ13614
  • ABRA1
  • ABRAXAS
• Synonyms name
  • Abraxas protein
• GenBank acession
  • AK023676
• Locus
  4q21.23
• Discovery year
  2006-04-03
• Entrez gene record
  84142
• Pubmed identfication
  • 12975309
  • 17525340
• RefSeq identity
  • NM_139076
• Classification
  • BRCA1 A complex
• VEGA ID
  OTTHUMG00000130429

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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