anti-CCDC98 Antibody

• Catalog number
  4321
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  CCDC98 Antibody: CCDC98, also known as Abraxas 1, was identified through protein binding studies using the breast and ovarian predisposition protein BRCA1 as the binding target. CCDC98 recruits RAP80, a ubiquitin-binding protein, to BRCA1, allowing the formation of BRCA1 foci in response to DNA damage caused by ionizing radiation. Both CCDC98 and RAP80 are required for DNA damage resistance, G2-M checkpoint control, and DNA repair. Cells depleted of either CCDC98 or RAP80 exhibited increased sensitivity to ionizing radiation, although not as much as in BRCA1-depleted cells, suggesting that CCDC98 and RAP80 control only part of the DNA damage response role of BRCA1. At least two isoforms of CCDC98 are known to exist.
• Gene names
  CCDC98 Antibody: ABRA1, CCDC98, ABRA1, UNQ496/PRO1013, BRCA1-A complex subunit Abraxas, Coiled-coil domain-containing protein 98
• Antibodie s label
  unlabelled serum
• Purity
  CCDC98 Antibody is affinity chromatography purified via peptide column.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Antigen
  CCDC98 antibody was made against a 15 amino acid synthetic peptide from near the amino terminus of human CCDC98.
• Immuno application
  ELISA, Western Blot, immuno-histo-chemistry
• Antibody advice
  CCDC98 antibody can be used for detection of CCDC98 by Western blot at 1 ug/mL. Antibody can also be used for immunohistochemistry starting at 5 ug/mL.
• Suspention pH azide
  CCDC98 Antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  CCDC98 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Works with
  Human, Mouse
• Omim nr
  109148531
• Ncbi nr
  NP_620775
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  84142
• GENE symbol
  FAM175A
• Antigene name
  family with sequence similarity 175, member A
• Source
  Homo sapiens
• Protein nr
  Q6UWZ7
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  CCDC98  
• Gene symbol
  ABRAXAS1
• Short name
  anti-CCDC98 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toCCDC98 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:25829
• Gene
  ABRAXAS1
• Long gene name
  abraxas 1, BRCA1 A complex subunit
• Synonyms gene
  • CCDC98
  • FAM175A
• Synonyms gene name
  • coiled-coil domain containing 98
  • family with sequence similarity 175, member A
  • family with sequence similarity 175 member A
  • Abraxas 1, BRCA1 A complex subunit
• Synonyms
  • FLJ13614
  • ABRA1
  • ABRAXAS
• Synonyms name
  • Abraxas protein
• GenBank acession
  • AK023676
• Locus
  4q21.23
• Discovery year
  2006-04-03
• Entrez gene record
  84142
• Pubmed identfication
  • 12975309
  • 17525340
• RefSeq identity
  • NM_139076
• Classification
  • BRCA1 A complex
• VEGA ID
  OTTHUMG00000130429

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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