NFkB Inducing Kinase NIK
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Catalog numberE8ER1913-80-Biotin
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PricePlease ask
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Size100ul
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ConjugationBiotin
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NoteFor research use only.
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GeneNF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) is a protein complex that controls transcription of DNA, cytokine production and cell survival. NF-κB is found in almost all animal cell types and is involved in cellular responses to stimuli such as stress, cytokines, free radicals, ultraviolet irradiation, oxidized LDL, and bacterial or viral antigens. NF-κB plays a key role in regulating the immune response to infection (κ light chains are critical components of immunoglobulins). Incorrect regulation of NF-κB has been linked to cancer, inflammatory and autoimmune diseases, septic shock, viral infection, and improper immune development. NF-κB has also been implicated in processes of synaptic plasticity and memory
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Gene target
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Gene symbolMAP4K4, MAP3K14
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Short nameNFkB Kinase NIK
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Alternative nameNFkB Inducing phosphorylation catalyst NIK
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Gene info
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Identity
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Gene
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Long gene namemitogen-activated protein kinase kinase kinase kinase 4
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1999-09-07
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Mitogen-activated protein kinase kinase kinase kinases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemitogen-activated protein kinase kinase kinase 14
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2000-08-11
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Mitogen-activated protein kinase kinase kinases
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VEGA ID
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Locus Specific Databases