Recombinant Rat REG4 Protein (Fc tag) 100µg

• Catalog number
  PKSR030288-100µg
• Price
  Please ask
• Size
  100µg

• Synonym
  REG4
• Activity
  NA
• Sequence
  Met1-Pro157
• Fusion tag
  C-Fc
• Accession
  Q68AX7
• ExpressedHost
  HEK293 Cells
• Shipping
  In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
• Purity
  > 80 % as determined by SDS-PAGE
• Endotoxin
  < 1.0 EU per μg of the protein as determined by the LAL method
• Stability and Storage
  Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Mol Mass
  42.9 kDa
• AP Mol Mass
  49 KDa
• Formulation
  Lyophilized from sterile PBS, pH 7.4
• Background
  Regenerating islet-derived protein 4, also known as REG-like protein, REG4, GISP and RELP, a member of the regenerating gene family belonging to the calcium (C-type) dependent lectin superfamily, has been found to be involved in malignancy in several different organs including the stomach, colorectum, pancreas and prostate. It is highly expressed in the gastrointestinal tract and markedly up-regulated in colon adenocarcinoma, pancreatic cancer, gastric adenocarcinoma, and inflammatory bowel disease. Expression of the Reg4 in different cell types has been associated with regeneration, cell growth and cell survival, cell adhesion and resistance to apoptosis. REG4 protein overexpression is associated with an unfavorable response to preoperative chemoradiotherapy and may be used as a predictive biomarker clinically. REG4 may play an important role in the development and progression of colorectal cancer, as well as in intestinal morphogenesis and epithelium restitution.
• Technical Data
• About
  Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
• Latin name
  Rattus norvegicus
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  REG4   Protein   tag   100µg  
• Gene symbol
  REG4
• Short name
  Recombinant REG4 Protein (Fc tag) 100µg
• Technique
  Recombinant, FC, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
• Host
  Rat
• Label
  Fc Tag
• Species
  Rat, Rats
• Alternative name
  Rec. Rat REG4 Protein (fragment c detection labelled) 100µg
• Alternative technique
  rec

Gene info

• Identity
  HGNC:22977
• Gene
  REG4
• Long gene name
  regenerating family member 4
• Synonyms gene name
  • regenerating islet-derived family, member 4
• Synonyms
  • REG-IV
  • RELP
  • GISP
• Synonyms name
  • regenerating gene type IV
  • gastrointestinal secretory protein
• GenBank acession
  • AY007243
• Locus
  1p12
• Discovery year
  2003-09-08
• Entrez gene record
  83998
• Pubmed identfication
  • 11311942
  • 12455032
• RefSeq identity
  • NM_032044
• Classification
  • C-type lectin domain containing
• VEGA ID
  OTTHUMG00000012175

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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