Recombinant Human ROR1 Protein (ECD, His Tag) 100µg
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Catalog numberPKSH030440-100µg
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PricePlease ask
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Size100µg
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SynonymdJ537F10.1;NTRKR1
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ActivityNA
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SequenceMet1-Glu403
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Fusion tagC-His
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AccessionNP_005003.2
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Expressed HostHEK293 Cells
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ShippingIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
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Purity>95 % as determined by SDS-PAGE.
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Endotoxin<1.0 EU per µg as determined by the LAL method.
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Stability and StorageSamples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Mol Mass43.4 kDa
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AP Mol Mass43.4 kDa
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FormulationLyophilized from sterile PBS, pH 7.4
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ReconstitutionPlease refer to it for detailed information.
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BackgroundReceptor tyrosine kinase-like orphan receptor 1 (ROR1), also known as neurotrophic tyrosine kinase, it is a member of the ROR family within receptor tyrosine kinases (RTK) superfamily. Human ROR1 is a type I transmembrane protein with 937 amino acids (aa) in length. It contains a 29 aa signal sequence, a 377 aa extracellular domain (ECD), a 21 aa transmembrane segment, and a 510 aa cytoplasmic region. ROR1 expressed strongly in human heart, lung and kidney, but weakly in the CNS. At developmental stage, it expressed at high levels during early embryonic development. ROR1 has been shown to have very low kinase activity in vitro and is unlikely to function as a tyrosine kinase in vivo. It may act as a receptor for wnt ligand WNT5A which may result in the inhibition of WNT3A-mediated signaling.
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Conjugationhistidine
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PropertiesHuman proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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SourceRecombinants or rec. proteins
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Grouprecombinants
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Gene target
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Gene symbolROR1, ROR1-AS1, ECD, RORA, SEM1
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Short nameRecombinant ROR1 Protein (ECD, His Tag) 100µg
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TechniqueRecombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
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LabelHis
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SpeciesHuman, Humans
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Alternative nameRec. H. sapiens ROR1 Protein (ECD, histidine detection labelled) 100µg
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Alternative techniquerec
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Gene info
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Identity
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Gene
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Long gene namereceptor tyrosine kinase like orphan receptor 1
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Synonyms gene
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GenBank acession
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Locus
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Discovery year2000-02-29
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- I-set domain containing
- Receptor tyrosine kinases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameROR1 antisense RNA 1
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Locus
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Discovery year2014-05-21
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Antisense RNAs
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameecdysoneless cell cycle regulator
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Synonyms gene name
- ecdysoneless homolog (Drosophila)
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Synonyms
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GenBank acession
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Locus
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Discovery year2006-02-06
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameRAR related orphan receptor A
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Synonyms gene name
- RAR-related orphan receptor A
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Synonyms
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GenBank acession
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Locus
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Discovery year1995-04-13
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- RAR related orphan receptors
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameSEM1 26S proteasome subunit
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Synonyms gene
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Synonyms gene name
- split hand/foot malformation (ectrodactyly) type 1
- chromosome 7 open reading frame 76
- SEM1, 26S proteasome complex subunit
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1991-08-20
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Transcription and export complex 2
- Proteasome
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VEGA ID
MeSH Data
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Name
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ConceptScope note: The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data