Recombinant Mouse CD155 / PVR Protein (His & Fc tag)

• Catalog number
  PKSM040774-50µg
• Price
  Please ask
• Size
  50µg

• Synonym
  3830421F03Rik;CD155;D7Ertd458e;HVED;mE4;necl-5;PVS;Taa1;Tage4
• Activity
  Measured by its binding ability in a functional ELISA. Immobilized mouse DNAM1 at 2 μg/ml (100 μl/well) can bind mouse CD155 with a linear ranger of 6.4-160 ng/ml.
• Sequence
  Met 1-Arg 345
• Fusion tag
  C-His & Fc
• Accession
  NA
• Expressed Host
  HEK293 Cells
• Shipping
  In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
• Purity
  > 90 % as determined by SDS-PAGE
• Endotoxin
  < 1.0 EU per μg of the protein as determined by the LAL method
• Stability and Storage
  Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Mol Mass
  63 kDa
• AP Mol Mass
  95-105 kDa
• Formulation
  Lyophilized from sterile PBS, pH 7.4
• Background
  CD155, commonly known as PVR (poliovirus receptor) and Necl-5 (nectin-like molecule-5), is a type I transmembrane single-span glycoprotein, and belongs to the nectins and nectin-like (Necl) subfamily. CD155 was originally identified based on its ability to mediate the cell attachment and entry of poliovirus (PV), an etiologic agent of the central nervous system disease poliomyelitis. The normal cellular function is in the establishment of intercellular adherens junctions between epithelial cells. CD155 may assist in an efficient humoral immune response generated within the intestinal immune system. It has been demonstrated that CD155 can be recognized and bond by DNAM-1 and CD96 which promote the adhension, migration and NK-cell killing, and thus efficiently prime cell-mediated tumor-specific immunity.Immune CheckpointImmune Checkpoint Detection: ELISA Antibodies   Immune Checkpoint Detection: ICC Antibodies   Immune Checkpoint Detection: IP Antibodies   Immune Checkpoint Detection: FCM Antibodies   Immune Checkpoint Detection: WB AntibodiesImmune Checkpoint ProteinsImmune Checkpoint Targets   Co-inhibitory Immune Checkpoint Targets Immunotherapy   Cancer Immunotherapy   Targeted Therapy
• Technical data
• Conjugation
  histidine
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  CD155   PVR   Protein   His   tag  
• Gene symbol
  PVR
• Short name
  Recombinant Mouse CD155 / PVR Protein (His & Fc tag)
• Technique
  Recombinant, Mouse, FC, mouses, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
• Host
  mouse
• Label
  His
• Species
  Mouse, Mouses
• Alternative name
  Rec. Mouse CD155 / poliovirus receptor Protein (histidine & fragment c detection labelled)
• Alternative technique
  rec, murine
• Alternative to gene target
  poliovirus receptor, CD155 and HVED and Necl-5 and NECL5 and PVS and TAGE4, PVR and IDBG-56486 and ENSG00000073008 and 5817, cell adhesion molecule binding, Extracellular, Pvr and IDBG-152745 and ENSMUSG00000040511 and 52118

Gene info

• Identity
  HGNC:9705
• Gene
  PVR
• Long gene name
  PVR cell adhesion molecule
• Synonyms gene
  • PVS
• Synonyms gene name
  • poliovirus receptor
• Synonyms
  • CD155
  • HVED
  • Necl-5
  • NECL5
  • Tage4
• Synonyms name
  • nectin-like 5
• GenBank acession
  • BC015542
• Locus
  19q13.31
• Discovery year
  2001-06-22
• Entrez gene record
  5817
• Pubmed identfication
  • 2170108
  • 28870470
• RefSeq identity
  • NM_006505
• Classification
  • Nectins and nectin-like molecules
  • CD molecules
  • C2-set domain containing
  • V-set domain containing
• VEGA ID
  OTTHUMG00000151527
• Locus Specific Databases
  • ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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