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Recombinant Mouse CD155 / PVR Protein (His & Fc tag) 100µg

  • Catalog number
    PKSM040774-100µg
  • Product name
    Recombinant Mouse CD155 / PVR Protein (His & Fc tag) 100µg
  • Size
    100µg
  • Activity
    Measured by its binding ability in a functional ELISA. Immobilized mouse DNAM1 at 2 μg/ml (100 μl/well) can bind mouse CD155 with a linear ranger of 6.4-160 ng/ml.
  • Synonym
    3830421F03Rik;CD155;D7Ertd458e;HVED;mE4;necl-5;PVS;Taa1;Tage4
  • Sequence
    Met 1-Arg 345
  • Fusion tag
    C-His & Fc
  • Accession
    NA
  • Expressed Host
    HEK293 Cells
  • Shipping
    In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
  • Purity
    > 90 % as determined by SDS-PAGE
  • Endotoxin
    < 1.0 EU per μg of the protein as determined by the LAL method
  • Stability and Storage
    Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Mol Mass
    63 kDa
  • AP Mol Mass
    95-105 kDa
  • Formulation
    Lyophilized from sterile PBS, pH 7.4
  • Background
    CD155, commonly known as PVR (poliovirus receptor) and Necl-5 (nectin-like molecule-5), is a type I transmembrane single-span glycoprotein, and belongs to the nectins and nectin-like (Necl) subfamily. CD155 was originally identified based on its ability to mediate the cell attachment and entry of poliovirus (PV), an etiologic agent of the central nervous system disease poliomyelitis. The normal cellular function is in the establishment of intercellular adherens junctions between epithelial cells. CD155 may assist in an efficient humoral immune response generated within the intestinal immune system. It has been demonstrated that CD155 can be recognized and bond by DNAM-1 and CD96 which promote the adhension, migration and NK-cell killing, and thus efficiently prime cell-mediated tumor-specific immunity.Immune CheckpointImmune Checkpoint Detection: ELISA Antibodies   Immune Checkpoint Detection: ICC Antibodies   Immune Checkpoint Detection: IP Antibodies   Immune Checkpoint Detection: FCM Antibodies   Immune Checkpoint Detection: WB AntibodiesImmune Checkpoint ProteinsImmune Checkpoint Targets   Co-inhibitory Immune Checkpoint Targets Immunotherapy   Cancer Immunotherapy   Targeted Therapy
  • Technical data
    Technical_data
  • Alternative to gene target
    • [ "poliovirus receptor", "CD155 and HVED and Necl-5 and NECL5 and PVS and TAGE4", "PVR and IDBG-56486 and ENSG00000073008 and 5817", "cell adhesion molecule binding", "Extracellular", "Pvr and IDBG-152745 and ENSMUSG00000040511 and 52118" ]
  • Gene target
    CD155 / PVR Protein His Fc tag 100µg
    • Gene info
    Locus Specific Databases:ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database
  • Gene symbol
    PVR
  • Host
    mouse
  • Short name
    Recombinant Mouse CD155 / PVR Protein (His & Fc tag) 100µg
  • Label
    His
  • label filter
    • His
  • technique filter
    • Recombinant
    • Mouse
    • FC
  • Technique
    Recombinant, Mouse, FC, mouses, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
  • Alternative technique
    rec, murine