Recombinant Mouse AGRP / AgRP Protein (His tag) 200µg

• Catalog number
  PKSM040762-200µg
• Price
  Please ask
• Size
  200µg

• Activity
  NA
• Synonym
  Agrt;Art
• Sequence
  Met 1-Thr 131
• Fusion tag
  C-His
• Accession
  P56473
• Expressed Host
  HEK293 Cells
• Shipping
  In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
• Purity
  > 80 % as determined by SDS-PAGE
• Endotoxin
  < 1.0 EU per μg of the protein as determined by the LAL method
• Stability and Storage
  Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Mol Mass
  13.7 kDa
• AP Mol Mass
  20 kDa
• Formulation
  Lyophilized from sterile PBS, pH 7.4
• Background
  Agouti Related Protein (AGRP, or AGRT), is an endogenous antagonist of the melanocortin receptors MC3R and MC4R found in the hypothalamus and exhibits potent orexigenic activity. AGRP can act as a competitive antagonist to proopiomelanocortin (POMC)-derived peptides at the melanocortin-4 receptor (MC4R), and that this homeostatic mechanism is important as a means of coordinating appetite with perceived metabolic requirement. AGRP is upregulated by fasting while intracerebroventricular injections of synthetic AGRP lead to increased appetite and food intake. Thus, AGRP is a powerful orexigenic peptide that increases food intake when ubiquitously overexpressed or when administered centrally.
• Technical data
• Conjugation
  histidine
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  AGRP   AgRP   Protein   His   tag   200µg  
• Gene symbol
  AGRP
• Short name
  Recombinant Mouse AGRP / AgRP Protein (His tag) 200µg
• Technique
  Recombinant, Mouse, mouses, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
• Host
  mouse
• Label
  His
• Species
  Mouse, Mouses
• Alternative name
  Rec. Mouse AGRP / AgRP Protein (histidine detection labelled) 200µg
• Alternative technique
  rec, murine

Gene info

• Identity
  HGNC:330
• Gene
  AGRP
• Long gene name
  agouti related neuropeptide
• Synonyms gene name
  • agouti (mouse) related protein
  • agouti related protein homolog (mouse)
• Synonyms
  • Agrt
  • ART
  • ASIP2
• GenBank acession
  • U88063
• Locus
  16q22.1
• Discovery year
  1998-06-22
• Entrez gene record
  181
• Pubmed identfication
  • 9119224
  • 9311920
• Classification
  • Neuropeptides
• VEGA ID
  OTTHUMG00000137509

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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