Recombinant Human AgRP / AGRP Protein (His tag) 20µg

• Catalog number
  PKSH031894-20µg
• Price
  Please ask
• Size
  20µg

• Synonym
  AGRT;ART;ASIP2
• Activity
  NA
• Sequence
  Met 1-Thr 132
• Fusion tag
  C-His
• Accession
  NP_001129.1
• Expressed Host
  HEK293 Cells
• Shipping
  In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
• Purity
  ＞90 % as determined by SDS-PAGE
• Endotoxin
  ＜1.0 EU per µg as determined by the LAL method
• Stability and Storage
  Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Mol Mass
  14 kDa
• AP Mol Mass
  16-19 kDa
• Formulation
  Lyophilized from sterile PBS, pH 7.2
• Reconstitution
  Please refer to it for detailed information.
• Background
  Agouti Related Protein (AGRP, or AGRT), is an endogenous antagonist of the melanocortin receptors MC3R and MC4R found in the hypothalamus and exhibits potent orexigenic activity. AGRP can act as a competitive antagonist to proopiomelanocortin (POMC)-derived peptides at the melanocortin-4 receptor (MC4R), and that this homeostatic mechanism is important as a means of coordinating appetite with perceived metabolic requirement. AGRP is upregulated by fasting while intracerebroventricular injections of synthetic AGRP lead to increased appetite and food intake. Thus, AGRP is a powerful orexigenic peptide that increases food intake when ubiquitously overexpressed or when administered centrally.
• Product URL
• PDF URL
• Conjugation
  histidine
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  AgRP   AGRP   Protein   His   tag   20µg  
• Gene symbol
  AGRP
• Short name
  Recombinant AgRP / AGRP Protein (His tag) 20µg
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
• Label
  His
• Species
  Human, Humans
• Alternative name
  Rec. H. sapiens AgRP / AGRP Protein (histidine detection labelled) 20µg
• Alternative technique
  rec

Gene info

• Identity
  HGNC:330
• Gene
  AGRP
• Long gene name
  agouti related neuropeptide
• Synonyms gene name
  • agouti (mouse) related protein
  • agouti related protein homolog (mouse)
• Synonyms
  • Agrt
  • ART
  • ASIP2
• GenBank acession
  • U88063
• Locus
  16q22.1
• Discovery year
  1998-06-22
• Entrez gene record
  181
• Pubmed identfication
  • 9119224
  • 9311920
• Classification
  • Neuropeptides
• VEGA ID
  OTTHUMG00000137509

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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