Recombinant Human SELM / Selenoprotein M Protein (His tag) 100µg

• Catalog number
  PKSH030612-100µg
• Price
  Please ask
• Size
  100µg

• Synonym
  SEPM
• Activity
  NA
• Sequence
  Ala 24-Leu 145
• Fusion tag
  C-His
• Accession
  Q8WWX9
• Expressed Host
  E. coli
• Shipping
  In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
• Purity
  ＞97 % as determined by SDS-PAGE
• Endotoxin
  Please contact us for more information.
• Stability and Storage
  Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Mol Mass
  15.4kDa
• AP Mol Mass
  19 kDa
• Formulation
  Lyophilized from sterile 50mM Tris, 50mM NaCl, 50mM Arg, 0.3% Tween 20, 5% glycerol, pH 8.5
• Reconstitution
  Please refer to it for detailed information.
• Background
  Selenoprotein M is a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine M is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This gene is expressed in a variety of tissues, and the protein is localized to the perinuclear structures. Selenoprotein M May function as a thiol-disulfide oxidoreductase that participates in disulfide bond formation. This protein is widely expressed and is highly expressed in brain. It is found in Cytoplasm, perinuclear region, Endoplasmic reticulum, Golgi apparatus. Localized to perinuclear structures corresponding to Golgi and endoplasmic reticulum. Experiments results have suggested that selenoprotein M may have an important role in protecting against oxidative damage in the brain and may potentially function in calcium regulation.
• Product URL
• PDF URL
• Conjugation
  histidine
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  SELM   Selenoprotein   Protein   His   tag   100µg  
• Gene symbol
  SELENOM
• Short name
  Recombinant SELM / Selenoprotein M Protein (His tag) 100µg
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
• Label
  His
• Species
  Human, Humans
• Alternative name
  Rec. H. sapiens SELM / Selenoprotein M Protein (histidine detection labelled) 100µg
• Alternative technique
  rec

Gene info

• Identity
  HGNC:30397
• Gene
  SELENOM
• Long gene name
  selenoprotein M
• Synonyms
  • SELM
  • SEPM
• Locus
  22q12.2
• Discovery year
  2016-09-18
• Entrez gene record
  140606
• Pubmed identfication
  • 11839807
• RefSeq identity
  • NM_080430
• Classification
  • Selenoproteins
• VEGA ID
  OTTHUMG00000151207

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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