Recombinant Human S100A3 / S100E Protein (His & MBP tag) 100µg

  • Catalog number
    PKSH031248-100µg
  • Price
    Please ask
  • Size
    100µg
  • Synonym
    S100E
  • Activity
    NA
  • Sequence
    Met 1-Gln 101
  • Fusion tag
    N-His & MBP
  • Accession
    P33764
  • Expressed Host
    E. coli
  • Shipping
    In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
  • Purity
    >95 % as determined by SDS-PAGE
  • Endotoxin
    Please contact us for more information.
  • Stability and Storage
    Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Mol Mass
    55.3 kDa
  • AP Mol Mass
    50 kDa
  • Formulation
    Lyophilized from sterile PBS, 20% glycerol, pH 7.4
  • Reconstitution
    Please refer to it for detailed information.
  • Background
    Protein S100-A3, also known as Protein S-100E, S100 calcium-binding protein A3, S100A3 and S100E, is a member of the S-100 family. S100A3 / S100E contains 2 EF-hand domains. S100A3 / S100E is highly expressed in the differentiating cuticular cells within the hair follicle and organized into mature hair cuticles. High concentrations of S100A3 homotetramer might provide the millimolar level of Ca2+ required for hair cuticular barrier formation. S100A3 / S100E is a unique member of the Ca2+-binding S100 protein family with the highest cysteine content and affinity for Zn2+. S100A3 / S100E binds both calcium and zinc. S100A3 / S100E probably binds 2 zinc ions per molecule. It may be involved in calcium-dependent cuticle cell differentiation and hair shaft formation. S100A3 plays an important role in calcium-dependent processes leading to hair shaft formation. S100A3 / S100E is a unique protein among all members of the calcium-binding S100 family, is specifically expressed at the inner endocuticle of human hair fibers. Upon hair damage, S100A3 / S100E is released from hair fibers and possibly destabilizes the hair tissue architecture.
  • Conjugation
    histidine
  • Properties
    Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
  • Source
    Recombinants or rec. proteins
  • Group
    recombinants
  • Gene target
    S100A3   S100E   Protein   His   MBP   tag   100µg  
  • Gene symbol
    S100A3, MBP, PRG2, ENO1, HIVEP2, HIVEP1
  • Short name
    Recombinant S100A3 / S100E Protein (His & MBP tag) 100µg
  • Technique
    Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
  • Label
    His
  • Species
    Human, Humans
  • Alternative name
    Rec. H. sapiens S100A3 / S100E Protein (histidine & MBP detection labelled) 100µg
  • Alternative technique
    rec
Gene info
  • Identity
  • Gene
  • Long gene name
    S100 calcium binding protein A3
  • Synonyms gene
  • Synonyms gene name
    • S100 calcium-binding protein A3
  • GenBank acession
  • Locus
  • Discovery year
    1993-10-04
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • S100 calcium binding proteins
  • VEGA ID
Gene info
Gene info
Gene info
Gene info
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: The initial culturing of cells derived directly from fresh TISSUES.
  • Tree numbers
    • E01.370.225.500.223.500
    • E05.200.500.265.500
    • E05.242.223.500
    • E05.481.500.249.500
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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