Recombinant Human PCBP1 Protein (His tag) 100µg

• Catalog number
  PKSH031057-100µg
• Price
  Please ask
• Size
  100µg

• Synonym
  HEL-S-85;hnRNP-E1;hnRNP-X;HNRPE1;HNRPX
• Activity
  NA
• Sequence
  Asp 2-Cys 356
• Fusion tag
  N-His
• Accession
  NP_006187.2
• Expressed Host
  E. coli
• Shipping
  In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
• Purity
  ＞87 % as determined by SDS-PAGE
• Endotoxin
  Please contact us for more information.
• Stability and Storage
  Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Mol Mass
  38.3 kDa
• AP Mol Mass
  42 kDa
• Formulation
  Lyophilized from sterile 50mM Tris, 500mM NaCl, 20% glycerol, pH 8.0
• Reconstitution
  Please refer to it for detailed information.
• Background
  Poly(rC)-binding protein 1, also known as Heterogeneous nuclear ribonucleoprotein E1, Alpha-CP1, Nucleic acid-binding protein SUB2.3 and PCBP1, is a family member of heterogeneous nuclear ribonucleoproteins (hnRNPs) that belong to RNA-binding proteins and bear three KH domains. PCBP1 is loosely bound in the nucleus. It may shuttle between the nucleus and the cytoplasm. It is abundantly expressed in skeletal muscle, thymus and peripheral blood leukocytes while a lower expression is observed in prostate, spleen, testis, ovary, small intestine, heart, liver, adrenal and thyroid glands. PCBP1 is widely expressed in many human tissues and involved in regulation of transcription, transportation process, and function of RNA molecules. PCBP1 plays a pivotal role in post-transcriptional regulation for RNA metabolism and RNA function in gene expression. PCBP1 acts as a negative regulator of CD44 variants splicing in HepG2 cells, and loss of PCBP1 in human hepatic tumor contributes to the formation of a metastatic phenotype.
• Product URL
• PDF URL
• Conjugation
  histidine
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  PCBP1   Protein   His   tag   100µg  
• Gene symbol
  PCBP1-AS1, PCBP1
• Short name
  Recombinant PCBP1 Protein (His tag) 100µg
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
• Label
  His
• Species
  Human, Humans
• Alternative name
  Rec. H. sapiens PCBP1 Protein (histidine detection labelled) 100µg
• Alternative technique
  rec

Gene info

• Identity
  HGNC:42948
• Gene
  PCBP1-AS1
• Long gene name
  PCBP1 antisense RNA 1
• Synonyms gene name
  • PCBP1 antisense RNA 1 (non-protein coding)
• Locus
  2p13.3
• Discovery year
  2011-09-08
• Entrez gene record
  400960
• Pubmed identfication
  • 28621149
• RefSeq identity
  • NR_033872
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000153728

Gene info

• Identity
  HGNC:8647
• Gene
  PCBP1
• Long gene name
  poly(rC) binding protein 1
• Synonyms gene name
  • poly(rC)-binding protein 1
• Synonyms
  • HNRPE1
  • hnRNP-E1
  • HNRPX
  • hnRNP-X
• Synonyms name
  • heterogeneous nuclear ribonucleoprotein E1
• Locus
  2p13.3
• Discovery year
  1996-06-07
• Entrez gene record
  5093
• Pubmed identfication
  • 8833161
• RefSeq identity
  • NM_006196
• Classification
  • Heterogeneous nuclear ribonucleoproteins
• VEGA ID
  OTTHUMG00000129645

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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