Recombinant Human EphB4 / HTK Protein (aa 563-987, His & GST tag) 50µg

• Catalog number
  PKSH030418-50µg
• Price
  Please ask
• Size
  50µg

• Synonym
  HTK;MYK1;TYRO11
• Activity
  The specific activity was determined to be 47 nmol/min/mg using Poly(Glu:Tyr) 4:1 as substrate.
• Sequence
  Leu563-Tyr987
• Fusion tag
  N-His & GST
• Accession
  P54760
• Expressed Host
  Baculovirus-Insect Cells
• Shipping
  Kinases are highly recommended to be shipped at frozen temperature with blue ice or dry ice.Shipment made at ambient temperature may seriously affect the activity of the ordered products.
• Purity
  ＞90 % as determined by SDS-PAGE
• Endotoxin
  ＜1.0 EU per µg as determined by the LAL method
• Stability and Storage
  Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Mol Mass
  75.2 kDa
• AP Mol Mass
  66 kDa
• Formulation
  Supplied as sterile 20mM Tris, 500mM NaCl, pH 8.0, 3mM DTT, 10% gly
• Reconstitution
  Please refer to it for detailed information.
• Background
  Ephrin type-B receptor 4 is a protein that in humans is encoded by the EPHB4 gene. It is a single-pass type I membrane protein belonging to the ephrin receptor subfamily of protein kinase superfamily. Members of the ephrin and Eph family are local mediators of cell function through largely contact-dependent processes in development and in maturity. Furthermore, EphB4 protein and the corresponding ligand Ephrin-B2 contribute to tumor growth in various human tumors. EphB4 protein has tumor suppressor activities and that regulation of cell proliferation, extracellular matrix remodeling, and invasive potential are important mechanisms of tumor suppression. Therefore, Ephrin-B2/EphB4 may be recognized as a novel prognostic indicator for cancers.
• Product URL
• PDF URL
• Conjugation
  histidine
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  EphB4   HTK   Protein   563-987   His   GST   tag   50µg  
• Gene symbol
  MGST3, EPHB4, MIR563, EFNB2
• Short name
  Recombinant EphB4 / HTK Protein (aa 563-987, His & GST tag) 50µg
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
• Label
  His
• Species
  Human, Humans
• Alternative name
  Rec. H. sapiens EphB4 / HTK Protein (aa 563-987, histidine & GST detection labelled) 50µg
• Alternative technique
  rec

Gene info

• Identity
  HGNC:7064
• Gene
  MGST3
• Long gene name
  microsomal glutathione S-transferase 3
• Synonyms
  • GST-III
• Synonyms name
  • microsomal glutathione S-transferase III
  • microsomal GST-3
  • microsomal GST-III
• GenBank acession
  • AF026977
• Locus
  1q24.1
• Discovery year
  1997-10-16
• Entrez gene record
  4259
• Pubmed identfication
  • 9278457
• RefSeq identity
  • NM_004528
• Classification
  • Microsomal glutathione S-transferases
• VEGA ID
  OTTHUMG00000034627

Gene info

• Identity
  HGNC:3395
• Gene
  EPHB4
• Long gene name
  EPH receptor B4
• Synonyms gene
  • HTK
• Synonyms gene name
  • EphB4
• Synonyms
  • Tyro11
• GenBank acession
  • AY056047
• Locus
  7q22.1
• Discovery year
  1994-12-15
• Entrez gene record
  2050
• Pubmed identfication
  • 8188704
• RefSeq identity
  • NM_004444
• Classification
  • EPH receptors
  • Sterile alpha motif domain containing
• VEGA ID
  OTTHUMG00000157040

Gene info

• Identity
  HGNC:32819
• Gene
  MIR563
• Long gene name
  microRNA 563
• Synonyms gene
  • MIRN563
• Synonyms
  • hsa-mir-563
• Locus
  3p25.1
• Discovery year
  2006-05-16
• Entrez gene record
  693148
• RefSeq identity
  • NR_030289
• Classification
  • MicroRNAs

Gene info

• Identity
  HGNC:3227
• Gene
  EFNB2
• Long gene name
  ephrin B2
• Synonyms gene
  • EPLG5
• Synonyms gene name
  • ephrin-B2
• Synonyms
  • LERK5
  • Htk-L
  • HTKL
  • MGC126226
  • MGC126227
  • MGC126228
• Synonyms name
  • HTK ligand
  • ligand of eph-related kinase 5
  • eph-related receptor tyrosine kinase ligand 5
• GenBank acession
  • L38734
• Locus
  13q33.3
• Discovery year
  1995-01-17
• Entrez gene record
  1948
• Pubmed identfication
  • 7833926
• RefSeq identity
  • NM_004093
• Classification
  • Ephrins
• VEGA ID
  OTTHUMG00000017324

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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