Recombinant Human C-C Motif Chemokine 16/CCL16 Protein 50µg
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Catalog numberPKSH032188-50µg
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PricePlease ask
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Size50µg
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SynonymC-C Motif Chemokine 16; Chemokine CC-4; HCC-4; Chemokine LEC; IL-10-Inducible Chemokine; LCC-1; Liver-Expressed Chemokine; Lymphocyte and Monocyte Chemoattractant; LMC; Monotactin-1; MTN-1; NCC-4; Small-Inducible Cytokine A16; CCL16; ILINCK; NCC4; SCYA16
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ActivityNA
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SequenceGln24-Gln120
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Fusion tagNA
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AccessionO15467
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Expressed HostE.coli
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ShippingThe product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
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Purity>95% as determined by reducing SDS-PAGE.
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Endotoxin<1.0 EU per µg as determined by LAL test.
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Stability and StorageLyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months
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Mol Mass11.0 kDa
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AP Mol Mass14 kDa
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FormulationLyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
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ReconstitutionPlease refer to it for detailed information.
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BackgroundCCL16 is a member of CC chemokine family. CCL16 cDNA encodes a 120 amino acid peptide along with a 23 amino acids signal peptide that is cleaved to generate 97 amino acid protein. CCL16 is distantly related to other CC chemokines, showing less than 30% sequence identity. CCL16 elicits its effects on cells by interacting with cell surface chemokine receptors such as CCR1, CCR2, CCR5 and CCR8. Recombinant CCL16 has been shown to chemoattract human monocytes and THP1 cells but not resting lymphocytes nor neutrophils. CCL16 has potent myelosuppressive activity, suppresses proliferation of myeloid progenitor cells. CCL16ninduces a calcium flux in THP1 cells that can be desensitized by prior exposure to RANTES, suggesting that CCL16 and RANTES share the same receptor in THP1 cells.
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DescriptionChemokines, chemokine receptors, ligands , motif chemokines and cytokines are supplied by Elabscience in 1.
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PropertiesHuman proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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SourceRecombinants or rec. proteins
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Grouprecombinants
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Gene target
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Gene symbolSMC4, PCK1, MYB, SFTPC, VCX3B, MAF, RFX1, EGR4, P4HA2
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Short nameRecombinant C-C Motif Chemokine 16/CCL16 Protein 50µg
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TechniqueRecombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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SpeciesHuman, Humans
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Alternative nameRec. H. sapiens C-C Motif Chemokine 16/CCL16 Protein 50µg
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Alternative techniquerec
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Gene info
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Identity
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Gene
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Long gene namestructural maintenance of chromosomes 4
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Synonyms gene
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Synonyms gene name
- SMC4 (structural maintenance of chromosomes 4, yeast)-like 1
- SMC4 structural maintenance of chromosomes 4-like 1 (yeast)
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Synonyms
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GenBank acession
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Locus
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Discovery year2001-02-22
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Entrez gene record
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Pubmed identfication
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Classification
- Structural maintenance of chromosomes proteins
- Condensin I subunits
- Condensin II subunits
- MicroRNA protein coding host genes
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namephosphoenolpyruvate carboxykinase 1
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Synonyms gene name
- phosphoenolpyruvate carboxykinase 1 (soluble)
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Synonyms
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Locus
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Discovery year1990-09-10
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Entrez gene record
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Pubmed identfication
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameMYB proto-oncogene, transcription factor
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Synonyms gene name
- v-myb avian myeloblastosis viral oncogene homolog
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Synonyms
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Locus
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Discovery year2001-06-22
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Entrez gene record
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Pubmed identfication
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Classification
- Myb/SANT domain containing
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namesurfactant protein C
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Synonyms gene
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Synonyms gene name
- surfactant, pulmonary-associated protein C
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Synonyms
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Synonyms name
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Locus
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Discovery year1988-05-11
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- BRICHOS domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namevariable charge X-linked 3B
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Synonyms
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Locus
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Discovery year2005-01-11
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Classification
- Variable charge X/Y family
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameMAF bZIP transcription factor
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Synonyms gene name
- v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
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Synonyms
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Locus
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Discovery year1991-08-01
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Entrez gene record
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Pubmed identfication
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Classification
- Basic leucine zipper proteins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameregulatory factor X1
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Synonyms gene name
- regulatory factor X, 1 (influences HLA class II expression)
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Synonyms
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Synonyms name
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Locus
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Discovery year1991-11-06
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Regulatory factor X family
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameearly growth response 4
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Synonyms
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Locus
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Discovery year1992-07-27
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Zinc fingers C2H2-type
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameprolyl 4-hydroxylase subunit alpha 2
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Synonyms gene name
- procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide II
- prolyl 4-hydroxylase, alpha polypeptide II
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1999-02-23
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- MicroRNA protein coding host genes
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VEGA ID
MeSH Data
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Name
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ConceptScope note: The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data