Rabbit Anti Human SRGN Antibody-Non-conjugated
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Catalog numberCSB-PA022664ESR2HU_100ul
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PricePlease ask
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Size100ul
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Long nameRabbit Antibody against Human SRGN, Non-conjugated
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Synonym nameSRGN Human Antibody
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Species reactivityHuman
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Tested applications recommended dilutionsELISA,WB,IHC;Recommended dilution:WB:1:500-2000,IHC:1:20-1:200
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ConjugationNon-conjugated
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Antibody isotypeIgG
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UniProt IDP10124
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FormatLiquid, diluted in buffer
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Buffer compositionPBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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Purity>95%
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Purification methodAntigen Affinity Purified Antibodies
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Antibody categoryPolyclonal Antibodies
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Immunogen typeRecombinant human Serglycin protein (28-158AA)
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Immunogen speciesHuman
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AliasHematopoietic proteoglycan core protein,Platelet proteoglycan core protein,Secretory granule proteoglycan core protein,SRGN,PRG,PRG1
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BackgroundPlays a role in formation of mast cell secretory granules and mediates storage of various compounds in secretory vesicles. Required for storage of some proteases in both connective tissue and mucosal mast cells and for storage of granzyme B in T-lymphocytes. Plays a role in localizing neutrophil elastase in azurophil granules of neutrophils. Mediates processing of MMP2. Plays a role in cytotoxic cell granule-mediated apoptosis by forming a complex with granzyme B which is delivered to cells by perforin to induce apoptosis. Regulates the secretion of TNF-alpha and may also regulate protease secretion. Inhibits bone mineralization.
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ClonalityPolyclonal antibody
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Shipping and storageSRGN Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
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PropertiesIf you buy Antibodies supplied by Cusabio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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AboutRabbits are used for polyclonal antibody production by Cusabio. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cusabio adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
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Latin nameOryctolagus cuniculus
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French translationanticorps
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Gene target
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Gene symbolSRGN
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Short nameAnti-SRGN
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Techniqueanti human, Antibody, Rabbit, anti, antibody to, anti human antibodies, antibodies against human proteins, antibodies for, antibody Conjugates
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HostRabbit, Rabbits
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SpeciesHuman, Humans
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Alternative nameSRGN Antibody
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Alternative techniqueantibodies, rabbit-anti
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Alternative to gene targetserglycin, PPG and PRG and PRG1, SRGN and IDBG-76481 and ENSG00000122862 and 5552, collagen binding, Extracellular, Srgn and IDBG-157635 and ENSMUSG00000020077 and 19073, BT.97928 and IDBG-629459 and ENSBTAG00000017863 and 509501
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Gene info
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Identity
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Gene
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Long gene nameserglycin
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Synonyms gene
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Synonyms gene name
- proteoglycan 1, secretory granule
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1988-07-22
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Entrez gene record
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RefSeq identity
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Classification
- Proteoglycans
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data