SRGN Antibody

• Catalog number
  bs-6789R
• Price
  Please ask
• Size
  0.1ml

• Long name
  SRGN Primary Polyclonal Antibody
• Also known as
  SRGN PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  SRGN
• Specificity
  This is a highly specific antibody against SRGN.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Serglycin/SRGN Polyclonal Antibody
• Gene ID number
  5552
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Plays a role in formation of mast cell secretory granules and mediates storage of various compounds in secretory vesicles. Required for storage of some proteases in both connective tissue and mucosal mast cells and for storage of granzyme B in T lymphocytes. Plays a role in localizing neutrophil elastase in azurophil granules of neutrophils. Mediates processing of MMP2. Plays a role in cytotoxic cell granule-mediated apoptosis by forming a complex with granzyme B which is delivered to cells by perforin to induce apoptosis. Regulates the secretion of TNF-alpha and may also regulate protease secretion. Inhibits bone mineralization.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  Chondroitin sulfate proteoglycan core protein; Cytolytic granule proteoglycan core protein; Hematopoetic proteoglycan core protein; Mastocytoma proteoglycan core protein; P.PG; PG19 core protein; Pgsg; Platelet proteoglycan core protein; platelet proteoglycan protein core; PLATELET PROTEOGLYCAN PROTEIN CORE; PPG; PRG; PRG1; PROTEOGLYCAN 1; proteoglycan 1, secretory granule; Proteoglycan 10K core protein; Proteoglycan peptide core protein; PROTEOGLYCAN PROTEIN CORE FOR MAST CELL SECRETORY GRANULE; secretory granule proteoglycan 1; Secretory granule proteoglycan core protein; Serglycin; serglycin proteoglycan; Sgc; Srgn; SRGN_HUMAN.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  SRGN  
• Gene symbol
  SRGN
• Short name
  Anti-SRGN
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  SRGN Polyclonal Antibody
• Alternative technique
  antibodies
• Alternative to gene target
  serglycin, PPG and PRG and PRG1, SRGN and IDBG-76481 and ENSG00000122862 and 5552, collagen binding, Extracellular, Srgn and IDBG-157635 and ENSMUSG00000020077 and 19073, BT.97928 and IDBG-629459 and ENSBTAG00000017863 and 509501

Gene info

• Identity
  HGNC:9361
• Gene
  SRGN
• Long gene name
  serglycin
• Synonyms gene
  • PRG
  • PRG1
• Synonyms gene name
  • proteoglycan 1, secretory granule
• Synonyms
  • PPG
• Synonyms name
  • serglycin proteoglycan
• GenBank acession
  • BC015516
• Locus
  10q22.1
• Discovery year
  1988-07-22
• Entrez gene record
  5552
• RefSeq identity
  • NM_002727
• Classification
  • Proteoglycans
• VEGA ID
  OTTHUMG00000018369

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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