Rabbit Anti Human PARD3 Antibody-Biotin
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Catalog numberCSB-PA819481LD01HU_50ug
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PricePlease ask
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Size50ug
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Long nameRabbit Antibody against Human PARD3, Biotin
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Synonym namePARD3 Human Antibody
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Species reactivityHuman
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Tested applications recommended dilutionsELISA
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ConjugationBiotin
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Antibody isotypeIgG
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UniProt IDQ8TEW0
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FormatLiquid, diluted in buffer
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Buffer compositionPreservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
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Purity>95%
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Purification methodProtein G purified
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Antibody categoryPolyclonal Antibodies
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Immunogen typeRecombinant human Partitioning defective 3 homolog protein (1068-1356AA)
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Immunogen speciesHuman
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AliasPartitioning defective 3 homolog,PAR-3,PARD-3,Atypical PKC isotype-specific-interacting protein,ASIP,CTCL tumor antigen se2-5,PAR3-alpha,PARD3,PAR3, PAR3A
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BackgroundAdapter protein involved in asymmetrical cell division and cell polarization processes. Seems to play a central role in the formation of epithelial tight junctions. Targets the phosphatase PTEN to cell junctions. Involved in Schwann cell peripheral myelination (By similarity). Association with PARD6B may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins. Required for establishment of neuronal polarity and normal axon formation in cultured hippocampal neurons.
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ClonalityPolyclonal antibody
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Shipping and storagePARD3 Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
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PropertiesIf you buy Antibodies supplied by Cusabio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Additional conjugationBiotinylated
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AboutRabbits are used for polyclonal antibody production by Cusabio. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cusabio adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
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Latin nameOryctolagus cuniculus
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French translationanticorps
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Gene target
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Gene symbolPARD3-DT, PARD3
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Short nameAnti-PARD3
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Techniqueanti human, Antibody, Rabbit, anti, antibody to, anti human antibodies, antibodies against human proteins, antibodies for
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HostRabbit, Rabbits
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LabelBiotin
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SpeciesHuman, Humans
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Alternative namePARD3 Antibody,Biotin conjugated
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Alternative techniqueantibodies, rabbit-anti
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Alternative to gene targetpar-3 partitioning defective 3 homolog (C. elegans), PARD3 and IDBG-69007 and ENSG00000148498 and 56288, phosphatidylinositol-4, Cell surfaces, Pard3 and IDBG-200951 and ENSMUSG00000025812 and 93742, PARD3 and IDBG-637236 and ENSBTAG00000014991 and 527964
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Gene info
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Identity
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Gene
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Long gene namePARD3 divergent transcript
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Synonyms gene
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Synonyms gene name
- PARD3 antisense RNA 1
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Locus
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Discovery year2012-12-20
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Entrez gene record
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Classification
- Divergent transcripts
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namepar-3 family cell polarity regulator
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Synonyms gene name
- par-3 (partitioning defective 3, C.elegans) homolog
- par-3 partitioning defective 3 homolog (C. elegans)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2001-07-27
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- PDZ domain containing
- Protein phosphatase 1 regulatory subunits
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data