Rabbit Anti Human MCM8 Antibody-HRP

• Catalog number
  CSB-PA890907LB01HU_50ug
• Price
  Please ask
• Size
  50ug

• Long name
  Rabbit Antibody against Human MCM8, HRP
• Synonym name
  MCM8 Human Antibody
• Species reactivity
  Human
• Tested applications recommended dilutions
  ELISA
• Conjugation
  HRP
• Antibody isotype
  IgG
• UniProt ID
  Q9UJA3
• Format
  Liquid, diluted in buffer
• Buffer composition
  Preservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
• Purity
  >95%
• Purification method
  Protein G purified
• Antibody category
  Polyclonal Antibodies
• Immunogen type
  Recombinant Human DNA helicase MCM8 protein (1-67AA)
• Immunogen species
  Human
• Alias
  DNA helicase MCM8,Minichromosome maintenance 8,MCM8,C20orf154
• Background
  Component of the MCM8-MCM9 complex, a complex involved in homologous recombination repair following DNA interstrand cross-links and plays a key role during gametogenesis. The MCM8-MCM9 complex probably acts as a hexameric helicase downstream of the Fanconi anemia proteins BRCA2 and RAD51 and is required to process aberrant forks into homologous recombination substrates and to orchestrate homologous recombination with resection, fork stabilization and fork restart. May also play a non-essential for DNA replication: may be involved in the activation of the prereplicative complex (pre-RC) during G(1) phase by recruiting CDC6 to the origin recognition complex (ORC). Binds chromatin throughout the cell cycle.
• Clonality
  Polyclonal antibody
• Shipping and storage
  MCM8 Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
• Short name of the antigen
  DNA helicase MCM8
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
• Properties
  If you buy Antibodies supplied by Cusabio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. HRP conjugates are often primary rabbit polyclonal antibodies couples to the enzyme horseradish peroxidase (HRP), found in the roots of horseradish. Also monoclonal HRP conjugates are often used for Western Blot. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Additional conjugation
  HRP Conjugated
• About
  Rabbits are used for polyclonal antibody production by Cusabio. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cusabio adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
• Latin name
  Oryctolagus cuniculus
• French translation
  anticorps

• Gene target
  MCM8  
• Gene symbol
  MCM8-AS1, MCM8
• Short name
  Anti-MCM8
• Technique
  anti human, Antibody, Rabbit, anti, antibody to, anti human antibodies, antibodies against human proteins, antibodies for
• Host
  Rabbit, Rabbits
• Label
  HRP
• Species
  Human, Humans
• Alternative name
  MCM8 Antibody,HRP conjugated
• Alternative technique
  antibodies, rabbit-anti

Gene info

• Identity
  HGNC:51230
• Gene
  MCM8-AS1
• Long gene name
  MCM8 antisense RNA 1
• GenBank acession
  • AK058185
• Locus
  20p12.3
• Discovery year
  2014-08-08
• Entrez gene record
  101929225
• RefSeq identity
  • NR_110101
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000186611

Gene info

• Identity
  HGNC:16147
• Gene
  MCM8
• Long gene name
  minichromosome maintenance 8 homologous recombination repair factor
• Synonyms gene
  • C20orf154
• Synonyms gene name
  • chromosome 20 open reading frame 154
  • minichromosome maintenance complex component 8
• Synonyms
  • MGC4816
  • MGC12866
  • MGC119522
  • MGC119523
  • dJ967N21.5
  • REC
• Synonyms name
  • REC homolog (Drosophila)
• GenBank acession
  • AJ439063
• Locus
  20p12.3
• Discovery year
  2001-07-17
• Entrez gene record
  84515
• Pubmed identfication
  • 12527764
• RefSeq identity
  • NM_032485
• Classification
  • MCM family
• VEGA ID
  OTTHUMG00000031822

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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