Rabbit Anti Human ITGA2B Antibody-Biotin
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Catalog numberCSB-PA011865LD01HU_100ug
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Price:
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Size100ug
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Long nameRabbit Antibody against Human ITGA2B, Biotin
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Synonym nameITGA2B Human Antibody
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Species reactivityHuman
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Tested applications recommended dilutionsELISA
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ConjugationBiotin
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Antibody isotypeIgG
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UniProt IDP08514
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FormatLiquid, diluted in buffer
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Buffer compositionPreservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
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Purity>95%
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Purification methodProtein G purified
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Antibody categoryPolyclonal Antibodies
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Immunogen typeRecombinant human Integrin alpha-IIb protein (639-887AA)
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Immunogen speciesHuman
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AliasGPalpha IIb,Platelet membrane glycoprotein IIb,CD41,GP2B, ITGAB,ITGA2B
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BackgroundIntegrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface.
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ClonalityPolyclonal antibody
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Shipping and storageITGA2B Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
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Short name of the antigenIntegrin alpha-IIb
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
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PropertiesIf you buy Antibodies supplied by Cusabio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Additional conjugationBiotinylated
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AboutRabbits are used for polyclonal antibody production by Cusabio. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cusabio adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
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Latin nameOryctolagus cuniculus
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French translationanticorps
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Gene target
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Gene symbolITGA2B
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Short nameAnti-ITGA2B
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Techniqueanti human, Antibody, Rabbit, anti, antibody to, anti human antibodies, antibodies against human proteins, antibodies for
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HostRabbit, Rabbits
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LabelBiotin
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SpeciesHuman, Humans
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Alternative nameITGA2B Antibody,Biotin conjugated
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Alternative techniqueantibodies, rabbit-anti
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Alternative to gene targetintegrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41), BDPLT16 and BDPLT2 and CD41 and CD41B and GP2B and GPIIb and GT and GTA and HPA3 and PPP1R93, ITGA2B and IDBG-53910 and ENSG00000005961 and 3674, fibrinogen binding, Cell surfaces, Itga2b and IDBG-212667 and ENSMUSG00000034664 and 16399, ITGA2B and IDBG-640964 and ENSBTAG00000008165 and 515011
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Gene info
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Identity
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Gene
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Long gene nameintegrin subunit alpha 2b
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Synonyms gene
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Synonyms gene name
- integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41B)
- integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
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Synonyms
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Synonyms name
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Locus
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Discovery year1986-01-01
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Entrez gene record
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Classification
- CD molecules
- Integrin alpha subunits
- Protein phosphatase 1 regulatory subunits
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data