• Catalog number
    CSB-PA011865LA01HU_50ug
  • Product name
    Rabbit Anti Human ITGA2B Antibody-Non-conjugated
  • Size
    50ug
  • Long name
    Rabbit Antibody against Human ITGA2B, Non-conjugated
  • Short name
    Anti-ITGA2B
  • Synonym name
    ITGA2B Human Antibody
  • Host
    Rabbit, Rabbits
  • Species reactivity
    Human
  • Tested applications recommended dilutions
    ELISA,IHC;Recommended dilution:IHC:1:20-1:200
  • Conjugation
    Non-conjugated
  • Antibody isotype
    IgG
  • UniProt ID
    P08514
  • Format
    Liquid, diluted in buffer
  • Buffer composition
    Preservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • Purity
    >95%
  • Purification method
    Protein G purified
  • Antibody category
    Polyclonal Antibodies
  • Immunogen type
    Recombinant human Integrin alpha-IIb protein (639-887AA)
  • Immunogen species
    Human
  • Alias
    GPalpha IIb,Platelet membrane glycoprotein IIb,CD41,GP2B, ITGAB,ITGA2B
  • Background
    Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface.
  • Clonality
    Polyclonal antibody
  • Shipping and storage
    ITGA2B Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
  • Short name of the antigen
    Integrin alpha-IIb
  • Alternative to gene target
    • [ "integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)", "BDPLT16 and BDPLT2 and CD41 and CD41B and GP2B and GPIIb and GT and GTA and HPA3 and PPP1R93", "ITGA2B and IDBG-53910 and ENSG00000005961 and 3674", "fibrinogen binding", "Cell surfaces", "Itga2b and IDBG-212667 and ENSMUSG00000034664 and 16399", "ITGA2B and IDBG-640964 and ENSBTAG00000008165 and 515011" ]
  • Gene target
    ITGA2B Non-conjugated
  • Gene info
  • Gene symbol
    ITGA2B
  • technique filter
    • anti human
    • Antibody
    • Rabbit
    • anti
  • Technique
    anti human, Antibody, Rabbit, anti, antibody to, anti human antibodies, antibodies against human proteins, antibodies for, antibody Conjugates
  • Alternative technique
    antibodies, rabbit-anti