Rabbit Anti Human HM13 Antibody-Biotin
-
Catalog numberCSB-PA851544LD01HU_100ug
-
PricePlease ask
-
Size100ug
-
-
Long nameRabbit Antibody against Human HM13, Biotin
-
Synonym nameHM13 Human Antibody
-
Species reactivityHuman
-
Tested applications recommended dilutionsELISA
-
ConjugationBiotin
-
Antibody isotypeIgG
-
UniProt IDQ8TCT9
-
FormatLiquid, diluted in buffer
-
Buffer compositionPreservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
-
Purity>95%
-
Purification methodProtein G purified
-
Antibody categoryPolyclonal Antibodies
-
Immunogen typeRecombinant human Minor histocompatibility antigen H13 protein (336-377AA)
-
Immunogen speciesHuman
-
AliasMinor histocompatibility antigen H13 (EC:3.4.23.-),HM13,H13,IMP1,PSL3,SPP,MSTP086,Intramembrane protease 1,IMP-1,IMPAS-1,hIMP1,Presenilin-like protein 3,Signal peptide peptidase
-
BackgroundCatalyzes intramembrane proteolysis of some signal peptides after they have been cleaved from a preprotein, resulting in the release of the fragment from the ER membrane into the cytoplasm. Required to generate lymphocyte cell surface (HLA-E) epitopes derived from MHC class I signal peptides (PubMed:11714810). May be necessary for the removal of the signal peptide that remains attached to the hepatitis C virus core protein after the initial proteolytic processing of the polyprotein (PubMed:12145199). Involved in the intramembrane cleavage of the integral membrane protein PSEN1 (PubMed:12077416, PubMed:11714810, PubMed:14741365). Cleaves the integral membrane protein XBP1 isoform 1 in a DERL1/RNF139-dependent manner (PubMed:25239945). May play a role in graft rejection (By similarity).
-
ClonalityPolyclonal antibody
-
Shipping and storageHM13 Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
-
DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
-
PropertiesIf you buy Antibodies supplied by Cusabio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
-
Additional conjugationBiotinylated
-
AboutRabbits are used for polyclonal antibody production by Cusabio. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cusabio adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
-
Latin nameOryctolagus cuniculus
-
French translationanticorps
-
Gene target
-
Gene symbolHM13-AS1, HM13-IT1, HM13
-
Short nameAnti-HM13
-
Techniqueanti human, Antibody, Rabbit, anti, antibody to, anti human antibodies, antibodies against human proteins, antibodies for
-
HostRabbit, Rabbits
-
LabelBiotin
-
SpeciesHuman, Humans
-
Alternative nameHM13 Antibody,Biotin conjugated
-
Alternative techniqueantibodies, rabbit-anti
-
Alternative to gene targethistocompatibility (minor) 13, HM13 and IDBG-62948 and ENSG00000101294 and 81502, aspartic endopeptidase activity, Cell surfaces, H13 and IDBG-209822 and ENSMUSG00000019188 and 14950, HM13 and IDBG-641527 and ENSBTAG00000008840 and 512534
-
Gene info
-
Identity
-
Gene
-
Long gene nameHM13 antisense RNA 1
-
Synonyms gene name
- HM13 antisense RNA 1 (non-protein coding)
-
Locus
-
Discovery year2011-05-19
-
Classification
- Antisense RNAs
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameHM13 intronic transcript 1
-
Synonyms gene name
- HM13 intronic transcript 1 (non-protein coding)
-
Locus
-
Discovery year2011-05-19
-
Classification
- Intronic transcripts
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namehistocompatibility minor 13
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year2001-09-17
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Peptidase family A22
-
VEGA ID
-
Locus Specific Databases
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data