Rabbit Anti Human CISH Antibody-Non-conjugated

• Catalog number
  CSB-PA885721ESR1HU_50ul
• Price
  Please ask
• Size
  50ul

• Long name
  Rabbit Antibody against Human CISH, Non-conjugated
• Synonym name
  CISH Human Antibody
• Species reactivity
  Human
• Tested applications recommended dilutions
  ELISA,IHC;Recommended dilution:IHC:1:20-1:200
• Conjugation
  Non-conjugated
• Antibody isotype
  IgG
• UniProt ID
  Q9NSE2
• Format
  Liquid, diluted in buffer
• Buffer composition
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Purity
  >95%
• Purification method
  Antigen Affinity Purified Antibodies
• Antibody category
  Polyclonal Antibodies
• Immunogen type
  Recombinant human Cytokine-inducible SH2-containing protein (1-257AA)
• Immunogen species
  Human
• Alias
  CIS,CIS-1,Protein G18,Suppressor of cytokine signaling,SOCS,CISH,G18
• Background
  SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. CIS is involved in the negative regulation of cytokines that signal through the JAK-STAT5 pathway such as erythropoietin, prolactin and interleukin 3 (IL3) receptor. Inhibits STAT5 trans-activation by suppressing its tyrosine phosphorylation. May be a substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
• Clonality
  Polyclonal antibody
• Shipping and storage
  CISH Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
• Properties
  If you buy Antibodies supplied by Cusabio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• About
  Rabbits are used for polyclonal antibody production by Cusabio. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cusabio adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
• Latin name
  Oryctolagus cuniculus
• French translation
  anticorps

• Gene target
  CISH   Non-conjugated  
• Gene symbol
  CISH
• Short name
  Anti-CISH
• Technique
  anti human, Antibody, Rabbit, anti, antibody to, anti human antibodies, antibodies against human proteins, antibodies for, antibody Conjugates
• Host
  Rabbit, Rabbits
• Species
  Human, Humans
• Alternative name
  CISH Antibody
• Alternative technique
  antibodies, rabbit-anti
• Alternative to gene target
  cytokine inducible SH2-containing protein, BACTS2 and CIS and CIS-1 and G18 and SOCS, CISH and IDBG-37175 and ENSG00000114737 and 1154, protein binding, Plasma membranes, Cish and IDBG-197065 and ENSMUSG00000032578 and 12700, CISH and IDBG-645783 and ENSBTAG00000022622 and 616753

Gene info

• Identity
  HGNC:1984
• Gene
  CISH
• Long gene name
  cytokine inducible SH2 containing protein
• Synonyms gene name
  • cytokine inducible SH2-containing protein
• Synonyms
  • CIS
  • G18
  • CIS-1
  • SOCS
• GenBank acession
  • Z77852
• Locus
  3p21.2
• Discovery year
  1996-09-23
• Entrez gene record
  1154
• Pubmed identfication
  • 9465889
  • 7796808
• RefSeq identity
  • NM_145071
• Classification
  • Suppressors of cytokine signaling
  • SH2 domain containing
• VEGA ID
  OTTHUMG00000156853

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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