Rabbit Anti Human ARHGEF18 Antibody-Non-conjugated
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Catalog numberCSB-PA05275A0Rb_50ug
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PricePlease ask
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Size50ug
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Long nameRabbit Antibody against Human ARHGEF18, Non-conjugated
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Synonym nameARHGEF18 Human Antibody
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Species reactivityHuman
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Tested applications recommended dilutionsELISA,WB;Recommended dilution:WB:1:1000-1:5000
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ConjugationNon-conjugated
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Antibody isotypeIgG
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UniProt IDQ6ZSZ5
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FormatLiquid, diluted in buffer
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Buffer compositionPreservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
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Purity>95%
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Purification methodProtein G purified
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Antibody categoryPolyclonal Antibodies
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Immunogen typeRecombinant human Rho guanine nucleotide exchange factor 18 protein (159-551AA)
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Immunogen speciesHuman
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AliasARHGEF18
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BackgroundRho GTPases are GTP binding proteins that regulate a wide spectrum of cellular functions. These cellular processes include cytoskeletal rearrangements, gene transcription, cell growth and motility. Activation of Rho GTPases is under the direct control of guanine nucleotide exchange factors (GEFs). p114RgoGEF cts as guanine nucleotide exchange factor (GEF) for RhoA GTPases. It may play a role in actin cytoskeleton reorganization in different tissues since its activation induces formation of actin stress fibers. It also act as a GEF for RAC1, inducing production of reactive oxygen species (ROS), but does not act as a GEF for CDC42. The G protein beta-gamma (Gbetagamma) subunits of heterotrimeric G proteins act as activators, explaining the integrated effects of LPA and other G-protein coupled receptor agonists on actin stress fiber formation, cell shape change and ROS production.
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ClonalityPolyclonal antibody
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Shipping and storageARHGEF18 Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
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Short name of the antigenRho guanine nucleotide exchange factor 18 protein
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
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PropertiesIf you buy Antibodies supplied by Cusabio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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AboutRabbits are used for polyclonal antibody production by Cusabio. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cusabio adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
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Latin nameOryctolagus cuniculus
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French translationanticorps
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Gene target
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Gene symbolARHGEF18-AS1, ARHGEF18
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Short nameAnti-ARHGEF18
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Techniqueanti human, Antibody, Rabbit, anti, antibody to, anti human antibodies, antibodies against human proteins, antibodies for, antibody Conjugates
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HostRabbit, Rabbits
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SpeciesHuman, Humans
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Alternative nameARHGEF18 Antibody
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Alternative techniqueantibodies, rabbit-anti
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Alternative to gene targetRho/Rac guanine nucleotide exchange factor (GEF) 18, ARHGEF18 and IDBG-22691 and ENSG00000104880 and 23370, Rho guanyl-nucleotide exchange factor activity, Cell surfaces
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Gene info
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Identity
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Gene
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Long gene nameARHGEF18 antisense RNA 1
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Locus
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Discovery year2020-10-14
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Classification
- Antisense RNAs
Gene info
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Identity
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Gene
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Long gene nameRho/Rac guanine nucleotide exchange factor 18
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Synonyms gene name
- rho/rac guanine nucleotide exchange factor (GEF) 18
- Rho/Rac guanine nucleotide exchange factor (GEF) 18
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2004-01-09
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Dbl family Rho GEFs
- Pleckstrin homology domain containing
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data