Toll Like Receptor 4 (TLR4) Monoclonal Antibody (Human, Rat)

• Catalog number
  MAA753Hu22-200ul
• Price
  Please ask
• Size
  200ul

• Description
  A Mouse monoclonal antibody against Human, Rat Toll Like Receptor 4 (TLR4)
• Specifications
  Host: Mouse; Species Reactivity: Human, Rat; Clonality: monoclonal; Tested applications: WB; Concentration: 1mg/mL; Isotype: IgG2a Kappa; Conjugation: Unconjugated
• Additional_information
  Sequence of the immunogen: Phe326~Ile634; Buffer composition: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Storage_and_shipping
  Upon receipt, store at -20°C or -80°C. Prepare working aliqotes prior to storage to avoid repeated freeze-thaw cycles.
• Notes
  Research Use Only.
• Properties
  If you buy Antibodies supplied by Cloud Clone Corp they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes. Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
• Latin name
  Rattus norvegicus
• Additional description
  The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
• French translation
  anticorps

• Gene target
  Toll   Like   Receptor   TLR4   Monoclonal  
• Gene symbol
  TLR4
• Short name
  Toll Like Receptor 4 (TLR4) Monoclonal Antibody ( , )
• Technique
  Antibody, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies
• Host
  Rat
• Species
  Rat, Humans, Rats
• Alternative name
  Toll Like Receptor 4 (toll-like receptor 4) monoclonal (antibody to-) (H. sapiens, Rat)
• Alternative technique
  antibodies
• Alternative to gene target
  toll-like receptor 4, ARMD10 and CD284 and TLR-4 and TOLL, TLR4 and IDBG-82738 and ENSG00000136869 and 7099, protein binding, Cell surfaces, Tlr4 and IDBG-156729 and ENSMUSG00000039005 and 21898, TLR4 and IDBG-638758 and ENSBTAG00000006240 and 281536

Gene info

• Identity
  HGNC:11850
• Gene
  TLR4
• Long gene name
  toll like receptor 4
• Synonyms gene name
  • toll-like receptor 4
• Synonyms
  • hToll
  • CD284
  • TLR-4
  • ARMD10
• GenBank acession
  • U88880
• Locus
  9q33.1
• Discovery year
  1998-06-25
• Entrez gene record
  7099
• Pubmed identfication
  • 9435236
  • 9237759
• RefSeq identity
  • NM_138554
• Classification
  • Toll like receptors
  • CD molecules
• VEGA ID
  OTTHUMG00000021046
• Locus Specific Databases
  • LRG_320

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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