TLR4/MD-2 Complex, TLR4 (Toll Like Receptor 4/MD-2, Toll Like Receptor 4)

• Catalog number
  MBS601832
• Price
  Please ask
• Size
  5x0.1 mg

• Products_type
  Antibody
• Products_short_name
  [TLR4/MD-2 Complex, TLR4]
• Products_name_syn
  [Anti -TLR4/MD-2 Complex, TLR4 (Toll Like Receptor 4/MD-2, Toll Like Receptor 4)]
• Other_names
  [toll-like receptor 4; Toll-like receptor 4; toll-like receptor 4]
• Other_gene_names
  [TLR4]
• Clonality
  Monoclonal
• Clone
  [4H273]
• Reactivity
  Mouse
• Specificity
  Recognizes mouse TLR4 (Toll Like Receptor 4). Preferentially recognizes TLR4-MD-2 complex than of TLR4 alone. Blocks activation of monocytes with LPS (7).
• Purity
  Affinity Purified Purified by Protein G affinity chromatography.
• Form
  Supplied as a liquid in PBS, 0.02% sodium azide.
• Storage_stability
  May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
• Tested_application
  Western Blot (WB), Immunoprecipitation (IP), Flow Cytometry (FC/FACS)
• Description
  The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

• Gene target
  TLR4/MD-2   Complex   TLR4   Toll   Like   Receptor   4/MD-2   Toll   Like   Receptor  
• Gene symbol
  LY96, LY86, TLR4, MIR1289-2, MIR521-2, MIR509-2, MIR512-2, MIR7-2, MIR329-2, RNU6-2
• Short name
  TLR4/MD-2 Complex, TLR4 (Toll Like Receptor 4/MD-2, Toll Like Receptor 4)
• Host
  Rat
• Isotype
  IgG2a
• Alternative name
  toll-like receptor 4/MD-2 aggregate, toll-like receptor 4 (Toll Like Receptor 4/MD-2, Toll Like Receptor 4)
• Alternative to gene target
  toll-like receptor 4, ARMD10 and CD284 and TLR-4 and TOLL, TLR4 and IDBG-82738 and ENSG00000136869 and 7099, protein binding, Cell surfaces, Tlr4 and IDBG-156729 and ENSMUSG00000039005 and 21898, TLR4 and IDBG-638758 and ENSBTAG00000006240 and 281536

Gene info

• Identity
  HGNC:17156
• Gene
  LY96
• Long gene name
  lymphocyte antigen 96
• Synonyms
  • MD-2
• GenBank acession
  • AB018549
• Locus
  8q21.11
• Discovery year
  2003-02-19
• Entrez gene record
  23643
• Pubmed identfication
  • 10359581
  • 11466383
• RefSeq identity
  • NM_015364
• VEGA ID
  OTTHUMG00000164504

Gene info

• Identity
  HGNC:16837
• Gene
  LY86
• Long gene name
  lymphocyte antigen 86
• Synonyms
  • MD-1
  • dJ80N2.1
• GenBank acession
  • AF057178
• Locus
  6p25.1
• Discovery year
  2003-02-19
• Entrez gene record
  9450
• Pubmed identfication
  • 9763566
• VEGA ID
  OTTHUMG00000014190

Gene info

• Identity
  HGNC:11850
• Gene
  TLR4
• Long gene name
  toll like receptor 4
• Synonyms gene name
  • toll-like receptor 4
• Synonyms
  • hToll
  • CD284
  • TLR-4
  • ARMD10
• GenBank acession
  • U88880
• Locus
  9q33.1
• Discovery year
  1998-06-25
• Entrez gene record
  7099
• Pubmed identfication
  • 9435236
  • 9237759
• RefSeq identity
  • NM_138554
• Classification
  • Toll like receptors
  • CD molecules
• VEGA ID
  OTTHUMG00000021046
• Locus Specific Databases
  • LRG_320

Gene info

• Identity
  HGNC:35282
• Gene
  MIR1289-2
• Long gene name
  microRNA 1289-2
• Synonyms gene
  • MIRN1289-2
• Synonyms
  • hsa-mir-1289-2
• Locus
  5q31.1
• Discovery year
  2008-11-03
• Entrez gene record
  100302134
• RefSeq identity
  • NR_031621
• Classification
  • MicroRNA MIR1289 family

Gene info

• Identity
  HGNC:32113
• Gene
  MIR521-2
• Long gene name
  microRNA 521-2
• Synonyms gene
  • MIRN521-2
• Synonyms
  • hsa-mir-521-2
• Locus
  19q13.42
• Discovery year
  2005-07-15
• Entrez gene record
  574481
• RefSeq identity
  • NR_030203
• Classification
  • MicroRNA MIR515 family

Gene info

• Identity
  HGNC:33641
• Gene
  MIR509-2
• Long gene name
  microRNA 509-2
• Synonyms gene
  • MIRN509-2
• Synonyms
  • hsa-mir-509-2
• Locus
  Xq27.3
• Discovery year
  2007-10-24
• Entrez gene record
  100126301
• RefSeq identity
  • NR_030586
• Classification
  • MicroRNA MIR506 family

Gene info

• Identity
  HGNC:32091
• Gene
  MIR512-2
• Long gene name
  microRNA 512-2
• Synonyms gene
  • MIRN512-2
• Synonyms
  • hsa-mir-512-2
• Locus
  19q13.42
• Discovery year
  2005-07-15
• Entrez gene record
  574459
• RefSeq identity
  • NR_030181
• Classification
  • MicroRNA MIR506 family

Gene info

• Identity
  HGNC:31639
• Gene
  MIR7-2
• Long gene name
  microRNA 7-2
• Synonyms gene
  • MIRN7-2
• Synonyms
  • hsa-mir-7-2
• Locus
  15q26.1
• Discovery year
  2004-04-23
• Entrez gene record
  407044
• RefSeq identity
  • NR_029606
• Classification
  • MicroRNA MIR7 family

Gene info

• Identity
  HGNC:32051
• Gene
  MIR329-2
• Long gene name
  microRNA 329-2
• Synonyms gene
  • MIRN329-2
• Synonyms
  • hsa-mir-329-2
• Locus
  14q32.31
• Discovery year
  2005-07-11
• Entrez gene record
  574409
• RefSeq identity
  • NR_029968
• Classification
  • MicroRNA MIR329 family

Gene info

• Identity
  HGNC:34270
• Gene
  RNU6-2
• Long gene name
  RNA, U6 small nuclear 2
• Synonyms
  • U6-2
• Locus
  19p13.3
• Discovery year
  2008-06-10
• Entrez gene record
  103625684
• Pubmed identfication
  • 12711679
• RefSeq identity
  • NR_125730
• Classification
  • Small nuclear RNAs

Similar products