Recombinant Thyroid Hormone Receptor Beta (THRb)
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Catalog numberRPA869Hu01
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Price:
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Size10ug
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SourceProkaryotic expression
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Predicted Molecular Mass KD28.6kDa
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Accurate Molecular Mass KDNA
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Organism speciesHomo sapiens (Human)
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Item NameThyroid Hormone Receptor Beta
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Alternative NamesERBA-BETA; ERBA2; GRTH; NR1A2; THR1; THRB1; THRB2; Erythroblastic Leukemia Viral(v-erb-a)Oncogene Homolog 2,Avian; Nuclear Receptor Subfamily 1,Group A,Member 2
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Research AreaSignal transduction;Endocrinology;Hormone metabolism;
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Buffer FormulationPBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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TraitsFreeze-dried powder
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Isoelectric Point6.5
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Purity≥ 95%
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Protein lengthTrp239~Glu457
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Tagtwo N-terminal Tags, His-tag and T7-tag
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Expression SystemProkaryotic expression
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ApplicationPositive Control; Immunogen; SDS-PAGE; WB.
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DescriptionHormone releasing factors and releasing hormones are signaling molecules produced by glands in multicellular organisms. The glands that secrete Luteinizing hormones LHRG and LH, FSH comprise the endocrine signaling system. The term growth hormone releasing hormone GHRH is sometimes extended to include chemicals produced by cells that affect the same cell (autocrine or intracrine signaling) or nearby cells (paracrine signaling). Human recombinant LHRG and GHRH are produced in E. coli or in yeast cells. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Additional sourceRecombinants or rec. proteins
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Grouprecombinants
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Gene target
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Gene symbolTHRB
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Short nameRecombinant Thyroid Hormone Receptor Beta (THRb)
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TechniqueRecombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Cloud Clone Corp advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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HostE.coli
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SpeciesHomo sapiens (Human)
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Alternative nameRec. Thyroid Hormone Receptor b (thyroid hormone receptor, b)
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Alternative techniquerec
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Alternative to gene targetthyroid hormone receptor, beta, C-ERBA-2 and C-ERBA-BETA and ERBA2 and GRTH and NR1A2 and PRTH and THR1 and THRB1 and THRB2, THRB and IDBG-22332 and ENSG00000151090 and 7068, thyroid hormone binding, nuclei, Thrb and IDBG-133569 and ENSMUSG00000021779 and 21834, THRB and IDBG-630420 and ENSBTAG00000017802 and 788329
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Tissuethyroid
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Gene info
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Identity
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Gene
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Long gene namethyroid hormone receptor beta
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Synonyms gene
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Synonyms gene name
- thyroid hormone receptor, beta (avian erythroblastic leukemia viral (v-erb-a) oncogene homolog 2)
- pituitary resistance to thyroid hormone
- thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian)
- thyroid hormone receptor, beta
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Synonyms
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Synonyms name
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Locus
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Discovery year1988-08-31
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Thyroid hormone receptors
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VEGA ID
MeSH Data
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Name
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ConceptScope note: The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data