Recombinant Platelet Derived Growth Factor Receptor Alpha (PDGFRa)
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Catalog number
RPC060Hu01
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Price
Please ask
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Size
430
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Source
Prokaryotic expression
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Predicted Molecular Mass KD
28.6kDa
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Accurate Molecular Mass KD
NA
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Organism species
Homo sapiens (Human)
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Item Name
Platelet Derived Growth Factor Receptor Alpha
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Alternative Names
CD140a; PDGFR2; Rhe-PDGFRA; CD140 antigen-like family member A; Platelet-derived growth factor receptor 2; Alpha-type platelet-derived growth factor receptor
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Research Area
Signal transduction;Infection immunity;Hematology;Kidney biomarker;
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Buffer Formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Traits
Freeze-dried powder
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Isoelectric Point
7.8
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Purity
≥ 95%
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Protein length
Ala170~Glu387
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Tag
two N-terminal Tags, His-tag and T7-tag
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Expression System
Prokaryotic expression
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Application
Positive Control; Immunogen; SDS-PAGE; WB.
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Description
The Recombinant Platelet Derived Growth Factor Receptor Alpha (PDGFRa) is a α- or alpha protein sometimes glycoprotein present in blood. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. Platelets, also called thrombocytes or cloth cells in blood and are needed to stop bleeding by clumping and clotting the blood the vessels when the an injury occurs. Teh bone marrow will produce the platelets that have no nucleus. Platelates are unique to mammals, the are curved shaped 1900nm to 3100 nm large nucleus free clothing structures. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Additional source
Recombinants or rec. proteins
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Group
recombinants
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Gene target
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Gene symbol
PDGFRA
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Short name
Recombinant Platelet Derived Growth Factor Receptor Alpha (PDGFRa)
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Technique
Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Cloud Clone Corp advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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Host
E.coli
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Species
Homo sapiens (Human)
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Alternative name
Rec. Platelet Derived Growth Factor Receptor a (platelet-derived growth factor receptor, a polypeptide)
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Alternative technique
rec
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Alternative to gene target
platelet-derived growth factor receptor, alpha polypeptide, CD140A and PDGFR-2 and PDGFR2 and RHEPDGFRA, PDGFRA and IDBG-18854 and ENSG00000134853 and 5156, transferase activity, nuclei, Pdgfra and IDBG-171929 and ENSMUSG00000029231 and 18595, PDGFRA and IDBG-642308 and ENSBTAG00000007173 and 282301
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Gene info
MeSH Data
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Name
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Concept
Scope note:
The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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