Recombinant Leukemia Inhibitory Factor (LIF)

Source

Prokaryotic expression
Predicted Molecular Mass KD

23.8kDa
Accurate Molecular Mass KD

NA
Organism species

Canis familiaris; Canine (Dog)
Item Name

Leukemia Inhibitory Factor
Alternative Names

CDF; D-FACTOR; HILDA; MLPLI; Cholinergic Differentiation Factor; Differentiation-Stimulating Factor; Melanoma-Derived LPL Inhibitor; Emfilermin
Research Area

Cytokine;Tumor immunity;Infection immunity;Neuro science;Bone metabolism;
Buffer Formulation

PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Traits

Freeze-dried powder
Isoelectric Point

9.5
Purity

≥ 95%
Protein length

Leu25~Ala196
Tag

two N-terminal Tags, His-tag and T7-tag
Expression System

Prokaryotic expression
Application

Positive Control; Immunogen; SDS-PAGE; WB.
Manual link
Description

Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.
Additional source

Recombinants or rec. proteins
Group

recombinants

Gene target

Leukemia Inhibitory Factor LIF
Gene symbol

LIF-AS1, LIF-AS2, LIF
Short name

Recombinant Leukemia Inhibitory Factor (LIF)
Technique

Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Cloud Clone Corp advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
Host

E.coli
Species

Canis familiaris; Canine (Dog)
Alternative name

Rec. Leukemia Inhibitory Factor (leukemia inhibitory factor)
Alternative technique

rec
Alternative to gene target

leukemia inhibitory factor, CDF and DIA and HILDA and MLPLI, LIF and IDBG-3968 and ENSG00000128342 and 3976, growth factor activity, Extracellular, Lif and IDBG-142317 and ENSMUSG00000034394 and 16878, LIF and IDBG-636335 and ENSBTAG00000007424 and 280840
Virus

leukemia

Identity

HGNC:6596
Gene

LIF
Long gene name

LIF interleukin 6 family cytokine
Synonyms gene name
- leukemia inhibitory factor
- LIF, interleukin 6 family cytokine
Synonyms
- CDF
- DIA
- HILDA
Synonyms name
Locus

22q12.2
Discovery year

1989-06-11
Entrez gene record

3976
Pubmed identfication
- 1714745
- 8058719
RefSeq identity
- NM_002309
Classification
- Receptor ligands
- Interleukin 6 type cytokine family
VEGA ID

OTTHUMG00000150910
Locus Specific Databases
- ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database

Name

Leukemia, Experimental
Concept

Scope note: Leukemia induced experimentally in animals by exposure to leukemogenic agents, such as VIRUSES; RADIATION; or by TRANSPLANTATION of leukemic tissues.
Tree numbers
- C04.557.337.372
- C04.619.531
- E05.598.500.496.500
Qualifiers

diagnosis, parasitology, immunology, microbiology, diagnostic imaging, physiopathology, rehabilitation, enzymology, etiology, mortality, epidemiology, blood, cerebrospinal fluid, chemically induced, congenital, diet therapy, drug therapy, therapy, psychology, urine, virology, history, classification, economics, embryology, genetics, nursing, radiotherapy, ethnology, prevention & control, pathology, metabolism, complications, surgery