Recombinant Interleukin 1 Receptor Antagonist (IL1RA)

• Catalog number
  RPA223Eq01
• Price
  Please ask
• Size
  10ug

• Source
  Prokaryotic expression
• Predicted Molecular Mass KD
  21.2kDa
• Accurate Molecular Mass KD
  NA
• Organism species
  Equus caballus; Equine (Horse)
• Item Name
  Interleukin 1 Receptor Antagonist
• Alternative Names
  IL1RN; IL1-RA; ICIL1RA; IL1ra3; IL1F3; IRAP;IL-1RA; Interleukin-1 Family Member 3; IL1 inhibitor; Anakinra
• Research Area
  Cytokine;Signal transduction;Infection immunity;
• Buffer Formulation
  PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Traits
  Freeze-dried powder
• Isoelectric Point
  8.8
• Purity
  ≥ 95%
• Protein length
  His26~Gln177
• Tag
  two N-terminal Tags, His-tag and T7-tag
• Expression System
  Prokaryotic expression
• Application
  Positive Control; Immunogen; SDS-PAGE; WB.
• Manual link
• Description
  The antagonist receptor ligand binding will be in contrast with agonist activity. Cloud Clone Corp produces more antagonist and receptor related products as 1. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Interleukin   Receptor   Antagonist   IL1RA  
• Gene symbol
  IL1R1, IL1RN
• Short name
  Recombinant Interleukin 1 Receptor Antagonist (IL1RA)
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Cloud Clone Corp advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Host
  E.coli
• Species
  Equus caballus; Equine (Horse)
• Alternative name
  Rec. Interleukin 1 Receptor Antagonist (IL1RA)
• Alternative technique
  rec

Gene info

• Identity
  HGNC:5993
• Gene
  IL1R1
• Long gene name
  interleukin 1 receptor type 1
• Synonyms gene
  • IL1R
  • IL1RA
• Synonyms gene name
  • interleukin 1 receptor, type I
• Synonyms
  • D2S1473
  • CD121A
• Synonyms name
  • interleukin-1 receptor, type I
• GenBank acession
  • M27492
• Locus
  2q11.2-q12.1
• Discovery year
  1990-06-27
• Entrez gene record
  3554
• Pubmed identfication
  • 1833184
  • 10191101
• Classification
  • I-set domain containing
  • Interleukin receptors
  • TIR domain containing
  • CD molecules
• VEGA ID
  OTTHUMG00000130783

Gene info

• Identity
  HGNC:6000
• Gene
  IL1RN
• Long gene name
  interleukin 1 receptor antagonist
• Synonyms
  • IL1RA
  • ICIL-1RA
  • IL1F3
  • IRAP
  • IL-1RN
  • MGC10430
• Synonyms name
  • interleukin-1 receptor antagonist protein
  • intracellular interleukin-1 receptor antagonist
• GenBank acession
  • M55646
• Locus
  2q14.1
• Discovery year
  1990-11-20
• Entrez gene record
  3557
• Pubmed identfication
  • 1386337
  • 8432529
• RefSeq identity
  • NM_173841
• Classification
  • Interleukins
  • Interleukin receptors
• VEGA ID
  OTTHUMG00000131341
• Locus Specific Databases
  • LRG_188

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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