OVA Conjugated Complement Component 5a Receptor 1 (C5aR1)
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Catalog number
CPB308Hu21
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Price
Please ask
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Size
500ug
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Source
Protein conjugation
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Predicted Molecular Mass KD
NA
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Accurate Molecular Mass KD
NA
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Organism species
Homo sapiens (Human)
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Item Name
Complement Component 5a Receptor 1
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Alternative Names
CD88; C5A; C5-AR1; C5R1; C5a anaphylatoxin chemotactic receptor 1
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Research Area
Signal transduction;Infection immunity;Immune molecule;
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Buffer Formulation
PBS, pH7.4.
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Traits
Freeze-dried powder
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Purity
> 90%
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Protein length
NA
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Tag
No tag
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Expression System
Protein Conjugation
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Application
Immunogen; SDS-PAGE; WB
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Gene
Ovalbumin (abbreviated OVA) is the main protein found in egg white, making up 60-65% of the total protein. Ovalbumin displays sequence and three-dimensional homology to the serpin superfamily, but unlike most serpins it is not a serine protease inhibitor. The function of ovalbumin is unknown, although it is presumed to be a storage protein. OVA is also the best characterized and the first antigen proteins used as a transgene to make transgenic mice. Many different transgenic mouse models have systemic OVA expression driven by the ubiquitously expressed b-actin promoter or tissue-specific OVA expression with insulin promoter to drive the transgene expression, for studying type I diabetes, or in different isoforms, secreted or cell-membrane associated, and more recently as inducible transgene models. These C57BL/6 mice, BALB/c mice models are well characterized, and have contributed to our understanding of immunogenicity and tolerance by the OVA model.
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Description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Gene target
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Short name
OVA Conjugated Complement Component 5a Receptor 1 (C5aR1)
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Technique
antibody Conjugates
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Host
chemical synthesis
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Species
Homo sapiens (Human)
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Alternative name
OVA coupled Complement Component 5a Receptor 1 (complement component 5a receptor 1)
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Alternative to gene target
complement component 5a receptor 1, C5A and C5AR and C5R1 and CD88, C5AR1 and IDBG-59445 and ENSG00000197405 and 728, C5a anaphylatoxin receptor activity, Cell surfaces, C5ar1 and IDBG-146297 and ENSMUSG00000049130 and 12273, BT.34208 and IDBG-639986 and ENSBTAG00000020872 and 101908388,493645
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