OVA Conjugated Complement Component 5a Receptor 1 (C5aR1)

• Catalog number
  CPB308Hu21-1MG
• Price
  Please ask
• Size
  1MG

• Description
  Recombinant Human Complement Component 5a Receptor 1 expressed in: chemical synthesis
• Specifications
  Host species: Homo sapiens (Human); Expression system: chemical synthesis; Expression region: Inquire; Purity: > 90%; Endotoxin level:
• Additional_information
  Uniprot ID: P21730; Buffer composition: PBS, pH 7.4.; Form: Freeze-dried powder; Predicted Molecular Mass (KD): Inquire; Isoelectric Point: Inquire
• Storage_and_shipping
  Shipped on ice packs. Upon receipt keep at 2-8 °C for up to 1 month. For long term storage prepare working aliquots and keep frozen at -20 or -80 °C. Avoid repeated freezing and thawing.
• Notes
  Research Use Only.
• Gene
  Ovalbumin (abbreviated OVA) is the main protein found in egg white, making up 60-65% of the total protein. Ovalbumin displays sequence and three-dimensional homology to the serpin superfamily, but unlike most serpins it is not a serine protease inhibitor. The function of ovalbumin is unknown, although it is presumed to be a storage protein. OVA is also the best characterized and the first antigen proteins used as a transgene to make transgenic mice. Many different transgenic mouse models have systemic OVA expression driven by the ubiquitously expressed b-actin promoter or tissue-specific OVA expression with insulin promoter to drive the transgene expression, for studying type I diabetes, or in different isoforms, secreted or cell-membrane associated, and more recently as inducible transgene models. These C57BL/6 mice, BALB/c mice models are well characterized, and have contributed to our understanding of immunogenicity and tolerance by the OVA model.
• Additional description
  The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

• Gene target
  OVA   Conjugated   Complement   Component   Receptor   C5aR1  
• Short name
  OVA Conjugated Complement Component 5a Receptor 1 (C5aR1)
• Technique
  antibody Conjugates
• Alternative name
  OVA coupled Complement Component 5a Receptor 1 (complement component 5a receptor 1)
• Alternative to gene target
  complement component 5a receptor 1, C5A and C5AR and C5R1 and CD88, C5AR1 and IDBG-59445 and ENSG00000197405 and 728, C5a anaphylatoxin receptor activity, Cell surfaces, C5ar1 and IDBG-146297 and ENSMUSG00000049130 and 12273, BT.34208 and IDBG-639986 and ENSBTAG00000020872 and 101908388,493645

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