OVA Conjugated Cholecystokinin A Receptor (CCKAR)
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Catalog number
CPA104Hu21-500ug
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Price
Please ask
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Size
500ug
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Description
Recombinant Human Cholecystokinin A Receptor expressed in: Protein conjugation
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Specifications
Host species: Homo sapiens (Human); Expression system: Protein conjugation; Expression region: Gly398InquireSer412; Purity: > 90%; Endotoxin level:
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Additional_information
Uniprot ID: P32238; Buffer composition: PBS, pH 7.4.; Form: Freeze-dried powder; Predicted Molecular Mass (KD): Inquire; Isoelectric Point: Inquire
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Storage_and_shipping
Shipped on ice packs. Upon receipt keep at 2-8 °C for up to 1 month. For long term storage prepare working aliquots and keep frozen at -20 or -80 °C. Avoid repeated freezing and thawing.
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Notes
Research Use Only.
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Gene
Ovalbumin (abbreviated OVA) is the main protein found in egg white, making up 60-65% of the total protein. Ovalbumin displays sequence and three-dimensional homology to the serpin superfamily, but unlike most serpins it is not a serine protease inhibitor. The function of ovalbumin is unknown, although it is presumed to be a storage protein. OVA is also the best characterized and the first antigen proteins used as a transgene to make transgenic mice. Many different transgenic mouse models have systemic OVA expression driven by the ubiquitously expressed b-actin promoter or tissue-specific OVA expression with insulin promoter to drive the transgene expression, for studying type I diabetes, or in different isoforms, secreted or cell-membrane associated, and more recently as inducible transgene models. These C57BL/6 mice, BALB/c mice models are well characterized, and have contributed to our understanding of immunogenicity and tolerance by the OVA model.
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Additional description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Gene target
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Gene symbol
CCKAR
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Short name
OVA Conjugated Cholecystokinin A Receptor (CCKAR)
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Technique
antibody Conjugates
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Alternative name
OVA coupled Cholecystokinin A Receptor (cholecystokinin A receptor)
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Alternative to gene target
cholecystokinin A receptor, CCK-A and CCK1-R and CCK1R and CCKRA, CCKAR and IDBG-12723 and ENSG00000163394 and 886, cholecystokinin receptor activity, Plasma membranes, Cckar and IDBG-164710 and ENSMUSG00000029193 and 12425, CCKAR and IDBG-641476 and ENSBTAG00000004988 and 506207
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Gene info
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