OVA Conjugated Cholecystokinin A Receptor (CCKAR)
-
Catalog number
CPA104Hu21
-
Price
Please ask
-
Size
10ug
-
-
Source
Protein conjugation
-
Predicted Molecular Mass KD
NA
-
Accurate Molecular Mass KD
NA
-
Organism species
Homo sapiens (Human)
-
Item Name
Cholecystokinin A Receptor
-
Alternative Names
CCK-A; CCK1; CCKRA; CCK1R; Cholecystokinin Type 1 Receptor
-
Research Area
Signal transduction;Endocrinology;Hepatology;Hormone metabolism;
-
Buffer Formulation
PBS, pH7.4.
-
Traits
Freeze-dried powder
-
Purity
> 90%
-
Protein length
Gly398-Ser412
-
Tag
N-terminal His Tag
-
Expression System
Protein conjugation
-
Application
Immunogen; SDS-PAGE; WB.
-
-
Gene
Ovalbumin (abbreviated OVA) is the main protein found in egg white, making up 60-65% of the total protein. Ovalbumin displays sequence and three-dimensional homology to the serpin superfamily, but unlike most serpins it is not a serine protease inhibitor. The function of ovalbumin is unknown, although it is presumed to be a storage protein. OVA is also the best characterized and the first antigen proteins used as a transgene to make transgenic mice. Many different transgenic mouse models have systemic OVA expression driven by the ubiquitously expressed b-actin promoter or tissue-specific OVA expression with insulin promoter to drive the transgene expression, for studying type I diabetes, or in different isoforms, secreted or cell-membrane associated, and more recently as inducible transgene models. These C57BL/6 mice, BALB/c mice models are well characterized, and have contributed to our understanding of immunogenicity and tolerance by the OVA model.
-
Description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
-
Gene target
-
Gene symbol
CCKAR
-
Short name
OVA Conjugated Cholecystokinin A Receptor (CCKAR)
-
Technique
antibody Conjugates
-
Host
Protein conjugation
-
Species
Homo sapiens (Human)
-
Alternative name
OVA coupled Cholecystokinin A Receptor (cholecystokinin A receptor)
-
Alternative to gene target
cholecystokinin A receptor, CCK-A and CCK1-R and CCK1R and CCKRA, CCKAR and IDBG-12723 and ENSG00000163394 and 886, cholecystokinin receptor activity, Plasma membranes, Cckar and IDBG-164710 and ENSMUSG00000029193 and 12425, CCKAR and IDBG-641476 and ENSBTAG00000004988 and 506207
-
Gene info
Similar products
