CLIA Kit for Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL)

  • Catalog number
    SCA855Ra
  • Price
    Please ask
  • Size
    1
  • Format
    48T, 96T, 96T×5, 96T×10, 96T×100
  • Detection range
    2.74-2,000pg/mL
  • Application
    Chemiluminescent immunoassay for Antigen Detection.
  • Organism species
    Rattus norvegicus (Rat)
  • Sensitivity
    The minimum detectable dose of this kit is typically less than 0.95pg/mL
  • Sample type
    Serum, plasma, tissue homogenates and other biological fluids
  • Assay length
    2h, 40min
  • Method
    Double-antibody Sandwich
  • Stability
    The stability of kit is determined by the loss rate of activity. The loss rate of this kit is less than 5% within the expiration date under appropriate storage condition. To minimize extra influence on the performance, operation procedures and lab conditions, especially room temperature, air humidity, incubator temperature should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same operator from the beginning to the end.
  • Alternative Names
    CD254; TNFSF11; ODF; OPGL; TRANCE; HRANKL2; SOdf; Tumor Necrosis Factor(ligand)superfamily Member 11; TNF-related activation-induced cytokine
  • Item Name
    Receptor Activator Of Nuclear Factor Kappa B Ligand
  • Research Area
    Signal transduction;Metabolic pathway;Apoptosis;Tumor immunity;Bone metabolism;
  • Description
    Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
  • Gene target
    CLIA   Kit   for   Receptor   Activator   Factor   Kappa   Ligand   RANkL  
  • Short name
    CLIA Kit for Receptor Activator Of Factor Kappa B Ligand (RANkL)
  • Alternative name
    CLIA reagent to measure Receptor Activator on Nuclear Factor Kappa B Ligand (RANkL)
  • Alternative technique
    kits
  • Alternative to gene target
    v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, C-Kit and CD117 and PBT and SCFR, KIT and IDBG-18980 and ENSG00000157404 and 3815, transferase activity, Extracellular, Kit and IDBG-172083 and ENSMUSG00000005672 and 16590, KIT and IDBG-642326 and ENSBTAG00000002699 and 280832
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