Eukaryotic Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL)

  • Catalog number
    RPU54822
  • Price
    Please ask
  • Size
    100 μg
  • Verified reactivity
    Mus musculus (Mouse)
  • Protein number
    O35235
  • Gene number
    Please refer to GenBank
  • Other name
    CD254; TNFSF11; ODF; OPGL; TRANCE; HRANKL2; SOdf; Tumor Necrosis Factor(ligand)superfamily Member 11; TNF-related activation-induced cytokine
  • Protein origin
    293F cell
  • Protein region
    Please contact us.
  • Protein sequence
    Please contact us.
  • Information about sequence
    Arg72~Asp316
  • Expected molecular weight
    35kDa
  • Protein purity
    ≥ 95%
  • Verified applications
    SDS-PAGE; WB; ELISA; IP; CoIP; EMSA; Reporter Assays; Purification; Amine Reactive Labeling.
  • Storage recommendation
    Aliquot and store at -20°C. Minimize freezing and thawing.
  • Use before
    1 year
  • Shipping requirements
    Blue ice
  • Estimated production time
    7-11 business days
  • Notes
    For research use only. Not for diagnostic procedures.
  • Description
    Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
  • Gene target
  • Short name
    Eukaryotic Receptor Activator Of Factor Kappa B Ligand (RANkL)
  • Label
    N-terminal His Tag
  • Alternative name
    Eukaryotic Receptor Activator on Nuclear Factor Kappa B Ligand (RANkL)
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